Carvacrol

  • Backbone: Monoterpene
  • Functional Group: Phenol

The anticonvulsant and anti-plasmid conjugation potential of Thymus vulgaris chemistry: An in vivo murine and in vitro study

Skalicka-Woźniak K, Walasek M, Aljarba TM, Stapleton P, Gibbons S, Xiao J, Łuszczki JJ Food and Chemical Toxicology, 2018 ABSTRACT: The high-performance counter-current chromatography was used for the efficient purification of single constituents from Thymus vulgaris essential oil. Mixtures of n-heptane, ethyl acetate, methanol, and water (5:2:5:2 and 4:1:4:1 v/v), allowed purification of eugenol, 1-octen-3-… Read more »

Oregano Essential Oil Attenuates RAW264.7 Cells from Lipopolysaccharide-Induced Inflammatory Response through Regulating NADPH Oxidase Activation-Driven Oxidative Stress

Cheng C, Zou Y, Peng J Molecules, 2018 ABSTRACT: Oregano is an aromatic plant widely distributed throughout the Mediterranean area and in Asia. Recent studies have revealed that the anti-inflammatory effect of essential oil in this plant. However, the mechanisms underlying the therapeutic potential have not been well elucidated. This study determined whether oregano essential… Read more »

Effects of Essential Oil of Satureja bachtiarica Bunge in a Rat Model of Reserpine-Induced Depression

Bakhtiarpoor M, Setorki M, Kaffashian MR Iran Journal of Medical Sciences, 2018 ABSTRACT: BACKGROUND: Due to the unfavorable side effects of some commonly used chemical drugs, the trend in the public has shifted towards using herbal medicines to treat central nervous system disorders like depression. The present experimental study was designed to evaluate the effect… Read more »

Transcriptomic approach and membrane fatty acid analysis to study the response mechanisms of Escherichia coli to thyme essential oil, carvacrol, 2-(E)-hexanal and citral exposure

Siroli L, Braschi G, De jong A, Kok J, Patrignani F, Lanciotti R Journal of Applied Microbiology, 2018 ABSTRACT: AIMS: The application of essential oils (EOs) and their components as food preservatives is promising but requires a deeper understanding of their mechanisms of action. This study aims to evaluate the effects of thyme EO, carvacrol,… Read more »

H2O2-Induced Oxidative Stress, AChE inhibition and mediated brain injury attenuated by Thymus algeriensis

Fatma G, Houda B, Ahmed L Applied Physiology, Nutrition, and Metabolism, 2018 ABSTRACT: The aim of the present study is to evaluate the acetylcholinesterase (AChE) inhibition, the antioxidant enzyme activities and malondialdehyde (MDA) levels induced by the hydrophobic fractions of Thymus algeriensis (HFTS) growing in Tunisia. The obtained results showed that Hydrogen peroxide (H2O2), an… Read more »

Chemical composition and antimicrobial activities of essential oil from Wedelia urticifolia growing wild in Hunan Province, China

Hu J, Jia M, Zhu L Natural Product Research, 2018 ABSTRACT: The essential oil obtained from Wedelia urticifolia growing in Hunan Province, China, was analyzed for the first time by capillary GC and GC-MS. A total of 67 constituents, representing 98.68% in essential oil were identified. The major constituents of the oil were: α-pinene (8.85%),… Read more »

Relaxant effect of Lippia origanoides essential oil in guinea-pig trachea smooth muscle involves potassium channels and soluble guanylyl cyclase

Menezes PMN, Brito MC, Paiva GO, Santos COD, Oliveira LM, Ribeiro LAA, Lima JT, Lucchese AM, Silva FS Journal of Ethnopharmacology, 2018 ABSTRACT: ETHNOPHARMACOLOGICAL RELEVANCE: Lippia origanoides H.B.K. is an aromatic species used in folk medicine to treat respiratory diseases, including asthma. AIM OF THE STUDY: The aim of this work was to evaluate the… Read more »

Terpenes, Phenylpropanoids, Sulfur and Other Essential Oil Constituents as Inhibitors of Cholinesterases

Politeo O, Burcul F, Blazevic I, Radan M Current Medicinal Chemistry, 2018 ABSTRACT: Essential oils constituents are a diverse family of low molecular weight organic compounds with comprehensive biological activity. According to their chemical structure these active compounds can be divided into four major groups: terpenes, terpenoids, phenylpropenes, and “others”. In addition, they may contain… Read more »

Citrus fruit extracts with carvacrol and thymol eliminated 7-log acid-adapted Escherichia coli O157:H7, Salmonella typhimurium, and Listeria monocytogenes: A potential of effective natural antibacterial agents

Chung D, Cho TJ, Rhee MS Food Research International, 2018 ABSTRACT: Despite the widespread belief that citrus fruit extracts (CFEs) are microbiologically safe due to their acidity, limited bactericidal effect results in low applicability as antibacterial agent and outbreaks occurred by acid-adapted pathogens. Here, we examined the antibacterial effects of CFEs [lime (Citrus medica), lemon… Read more »