Cinnamaldehyde

  • Backbone: Monoterpene
  • Functional Group: Aldehyde

Structure-activity modelling of essential oils, their components, and key molecular parameters and descriptors

Owen L, Laird K, Wilson PB Molecular and Cellular Probes, 2017 ABSTRACT: Many essential oil components are known to possess broad spectrum antimicrobial activity, including against antibiotic resistant bacteria. These compounds may be a useful source of new and novel antimicrobials. However, there is limited research on the structure-activity relationship (SAR) of essential oil compounds,… Read more »

Cinnamomum zeylanicum bark essential oil induces cell wall remodelling and spindle defects in Candida albicans

Shahina Z, El-Ganiny AM, Minion J, Whiteway M, Sultana T, Dahms TES Fungal Biology and Biotechnology, 2018 ABSTRACT: BACKGROUND: Cinnamon (Cinnamomum zeylanicum) bark extract exhibits potent inhibitory activity against Candida albicans but the antifungal mechanisms of this essential oil remain largely unexplored. RESULTS: We analyzed the impact of cinnamon bark oil on C. albicans RSY150,… Read more »

The Neuroprotective Effects of Cinnamic Aldehyde in an MPTP Mouse Model of Parkinson’s Disease

Bae WY, Choi JS, Jeong JW International Journal of Molecular Sciences, 2018 ABSTRACT: Cinnamic aldehyde (CA), a key flavor compound in cinnamon essential oil, has been identified as an anti-oxidant, anti-angiogenic, and anti-inflammatory material. Recently, the neuroprotective effects of CA have been reported in various neurodegenerative disorders, including Parkinson’s disease (PD). In neurons, autophagy is… Read more »

Anti-inflammatory effect of cinnamaldehyde and linalool from the leaf essential oil of Cinnamomum osmophloeum Kanehira in endotoxin-induced mice

Lee SC, Wang SY, Li CC, Liu CT Journal of Food and Drug Analysis, 2018 ABSTRACT: Cinnamomum osmophloeum Kanehira is a Taiwan native plant that belongs to genus Cinnamomum and is also known as pseudocinnamomum or indigenous cinnamon. Its leaf is traditionally used by local people in cooking and as folk therapy. We previously demonstrated… Read more »

Antifungal and Anti-Biofilm Activity of Essential Oil Active Components against Cryptococcus neoformans and Cryptococcus laurentii

Kumari P, Mishra R, Arora N, Chatrath A, Gangwar R, Roy P, Prasad R Frontiers in Microbiology, 2017 ABSTRACT: Cryptococcosis is an emerging and recalcitrant systemic infection occurring in immunocompromised patients. This invasive fungal infection is difficult to treat due to the ability of Cryptococcus neoformans and Cryptococcus laurentii to form biofilms resistant to standard antifungal treatment…. Read more »

Chemistry, Antimicrobial Mechanisms, and Antibiotic Activities of Cinnamaldehyde against Pathogenic Bacteria in Animal Feeds and Human Foods

Friedman M Journal of Agricultural and Food Chemistry, 2017 ABSTRACT: Cinnamaldehyde is a major constituent of cinnamon essential oils produced by aromatic cinnamon plants. This compound has been reported to exhibit antimicrobial properties in vitro in laboratory media and in animal feeds and human foods contaminated with disease-causing bacteria including Bacillus cereus, Campylobacter jejuni, Clostridium perfringens, Escherichia… Read more »

In vitro Protoscolicidal Effects of Cinnamomum zeylanicum Essential Oil and Its Toxicity in Mice

Mahmoudvand H, Mahmoudvand H, Oliaee RT, Kareshk AT, Mirbadie SR, Aflatoonian MR Pharmacognosy Magazine, 2017 BACKGROUND: This study investigates the scolicidal effects of Cinnamomum zeylanicum essential oilagainst the protoscoleces of hydatid cysts and its toxicity in the mice model. MATERIALS AND METHODS: Gas chromatography/mass spectroscopy analyses were used to identify the constituents of essential oil. Protoscoleces were treated… Read more »

Inhibitory effects of cinnamon and clove essential oils on mold growth on baked foods

Ju J, Xu X, Xie Y, Guo Y, Cheng Y, Qian H, Yao W Food Chemistry, 2017 ABSTRACT: This study evaluated the minimum inhibition concentration (MIC) and minimum lethal concentration (MLC) of cinnamon and clove essential oils against mold growth on green bean cake and finger citron crisp cake, and also examined the effects of these two essential… Read more »

Evaluation of active ingredients and larvicidal activity of clove and cinnamon essential oils against Anopheles gambiae (sensu lato)

Thomas A, Mazigo HD, Manjurano A, Morona D, Kweka EJ Parasites & Vectors, 2017 BACKGROUND: Mosquitoes are well-known vectors of many diseases including malaria and lymphatic filariasis. Uses of synthetic insecticides are associated with high toxicity, resistance, environmental pollution and limited alternative, effective synthetic insecticides. This study was undertaken to evaluate the larvicidal efficacy of… Read more »

Repeated systemic administration of the cinnamon essential oil possesses anti-anxiety and anti-depressant activities in mice

Sohrabi R, Pazgoohan N, Seresht HR, Amin B Iranian Journal of Basic Medical Science, 2017 OBJECTIVES: The present study aimed to evaluate the putative antidepressant and anti-anxiety effects of the cinnamon essential oil when administered acute (for 3 doses) and sub-acute (for 14 days) to mice. MATERIALS AND METHODS: In an acute experimental study, forced swim test… Read more »