Endocrine System

This system includes the pituitary gland, pineal gland, hypothalamus, thyroid, parathyroid, pancreas, adrenal glands, testes and ovaries. Common disorders include diabetes, osteoporosis, thyroid disorders, and sex hormone imbalance.

AMPK Activation Mediated by Hinokitiol Inhibits Adipogenic Differentiation of Mesenchymal Stem Cells through Autophagy Flux

Lee JH, Jeong JK, Park SY International Journal of Endocrinology, 2018 ABSTRACT: BACKGROUND AND PURPOSE: Hinokitiol, a natural monopenoid present in the essential oil of Calocedrus formosana heartwood, exerts potent anticancer, anti-inflammatory, antibacterial, and neuroprotective effects on various cells. However, the antiobesity effect of hinokitiol on adipocytes is unclear. EXPERIMENTAL APPROACH: In this study, we… Read more »

Pinus Roxburghii essential oil anticancer activity and chemical composition evaluation

Sajid A, Manzoor Q, Iqbal M, Tyagi AK, Sarfraz RA, Sajid A EXCLI Journal, 2018 ABSTRACT: The present study was conducted to appraise the anticancer activity of Pinus roxburghii essential oil along with chemical composition evaluation. MTT assay revealed cytotoxicity induction in colon, leukemia, multiple myeloma, pancreatic, head and neck and lung cancer cells exposed… Read more »

The Wound Healing Effects of Herbal Cream Containing Oliveria Decumbens and Pelargonium Graveolens Essential Oils in Diabetic Foot Ulcer Model

Mahboubi M, Taghizadeh M, Khamechian T, Tamtaji OR, Mokhtari R, Talaei SA World Journal of Plastic Surgery, 2018 ABSTRACT: BACKGROUND: The number of diabetic patients in adult population is increasing. All this population are at risk of developing diabetic foot ulcers (DFUs) that are associated with unwanted ailments and high mortality. In spite of current… Read more »

Rhaponticum acaule (L) DC essential oil: chemical composition, in vitro antioxidant and enzyme inhibition properties

Mosbah H, Chahdoura H, Kammoun J, Hlila MB, Louati H, Hammami S, Flamini G, Achour L, Selmi B BMC Complementary and Alternative Medicine, 2018 ABSTRACT: BACKGROUND: α-glucosidase is a therapeutic target for diabetes mellitus (DM) and α-glucosidase inhibitors play a vital role in the treatments for the disease. Furthermore, xanthine oxidase (XO) is a key… Read more »

Citrus essential oils inhalation by mice: Behavioral testing, GCMS plasma analysis, corticosterone, and melatonin levels evaluation.

Wolffenbüttel AN, Zamboni A, Becker G, Dos Santos MK, Borille BT, de Cássia Mariotti K, Fagundes AC, de Oliveira Salomón JL, Coelho VR, Ruiz LV, de Moura Linck V, Dallegrave E, Cano P, Esquifino AI, Leal MB, Limberger RP Phytotherapy Research, 2017 ABSTRACT: The use of orange essential oils (EOs) as a complementary treatment is very common… Read more »

iTRAQ Proteomic Analysis Reveals That Metabolic Pathways Involving Energy Metabolism Are Affected by Tea Tree Oil in Botrytis cinerea

Xu J, Shao X, Wei Y, Xu F, Wang H Frontiers in Microbiology, 2017 ABSTRACT: Tea tree oil (TTO) is a volatile essential oil obtained from the leaves of the Australian tree Melaleuca alternifolia by vapor distillation. Previously, we demonstrated that TTO has a strong inhibitory effect on Botrytis cinerea. This study investigates the underlying antifungal mechanisms at the molecular… Read more »

Cytotoxic and genotoxic potential of geraniol in peripheral blood mononuclear cells and human hepatoma cell line (HepG2)

Queiroz TB, Santos GF, Ventura SC, Hiruma-Lima CA, Gaivão IOM, Maistro EL Genetics and Molecular Research, 2017 ABSTRACT: Geraniol is an acyclic monoterpene alcohol present in the essential oil of many aromatic plants and is one of the most frequently used molecules by the flavor and fragrance industries. The literature also reports its therapeutic potential, highlighting itself… Read more »

Peppermint essential oil alleviates hyperglycemia caused by streptozotocin- nicotinamide-induced type 2 diabetes in rats

Abdellatief SA, Beheiry RR, El-Mandrawy SAM Biomedicine and Pharmacotherapy, 2017 ABSTRACT: The prevalence of diabetes mellitus is steadily growing throughout the world. Traditional medicine has an excellent potential in the treatment of diabetes mellitus. The present study was undertaken to evaluate the potential antidiabetic effect of peppermint essential oil (PEO) on streptozotocin (STZ) and nicotinamide induced diabetic… Read more »

Rosemary (Rosmarinus officinalis) essential oil components exhibit anti-hyperglycemic, anti-hyperlipidemic and antioxidant effects in experimental diabetes

Selmi S, Rtibi K, Grami D, Sebai H, Marzouki L Pathophysiology, 2017 INTRODUCTION: The present study aims to investigate the protective effects of Rosemary (Rosmarinus officinalis L.) essential oils (ROEO) against alloxan-induced diabetes and oxidative stress in rats. METHODS: The animals were divided into four groups: Healthy Control (HC); Diabetic Control (DC); Healthy+ROEO (H+ROEO) and Diabetic+ROEO (D+ROEO)…. Read more »

Hepatotoxicity of monoterpenes and sesquiterpenes

Zárybnický T, Boušová I, Ambrož M, Skálová L Archives of Toxicology, 2017 ABSTRACT: Public interest in natural therapies has increased significantly over past decades. Herbs and herbal products are extensively consumed worldwide and they are generally considered as safe. However, this may not always be true as many cases of herb-induced liver injury are reported… Read more »