Linalool

  • Backbone: Monoterpene
  • Functional Group: Alcohol

Neuron differentiation-related genes are up-regulated in the hypothalamus of odorant-inhaling rats subjected to acute restraint stress.

Nakamura A, Fujiwara S, Ishijima T, Okada S, Nakai Y, Matsumoto I, Misaka T, Abe K Journal of agricultural and food chemistry, 2010 ABSTRACT: To elucidate some physiopsychological effects of a pleasant odor, we analyzed gene expression profiles in the hypothalamus of rats which, under a restraint-stressed condition, inhaled (R)-(-)-linalool. Consequently, 697 probe sets showed… Read more »

Stress repression in restrained rats by (R)-(-)-linalool inhalation and gene expression profiling of their whole blood cells

Nakamura A, Fujiwara S, Matsumoto I, Abe K Journal of agricultural and food chemistry, 2009 ABSTRACT: As an attempt to quantitatively analyze the physiopsychological effects elicited by odorants, white blood cells and gene expression were profiled in the whole blood of the rats exposed to (R)-(-)-linalool during restraint stress for 2 h. In neutrophils and… Read more »

Inhaled linalool-induced sedation in mice

Linck VM, da Silva AL, Figueiró M, Piato AL, Herrmann AP, Dupont Birck F, Caramão EB, Nunes DS, Moreno PR, Elisabetsky E Phytomedicine : international journal of phytotherapy and phytopharmacology ABSTRACT: Linalool is a monoterpene often found as a major component of essential oils obtained from aromatic plant species, many of which are used in… Read more »

Patch Testing with Main Sensitizers Does Not Detect All Cases of Contact Allergy to Oxidized Lavender Oil

Hagvall L, Christensson JB Acta dermato-venereologica, 2016 ABSTRACT: Lavender oil is an essential oil obtained from lavender (Lavendula angustifolia). The main components linalool and linalyl acetate have been shown to autoxidize in contact with oxygen in the air, forming sensitizing hydroperoxides. Patients with suspected allergic contact dermatitis were consecutively patch-tested with oxidized lavender oil 6%… Read more »

Ocimum basilicum: Antibacterial activity and association study with antibiotics against bacteria of clinical importance

Araújo SV, Pereira SJ, de Luna FPH, Fernanda RFA, Douglas MCH, Beuttenmuller NAL, Oliveira LE Pharmaceutical biology, 2016 ABSTRACT: Ocimum basilicum: Antibacterial activity and association study with antibiotics against bacteria of clinical importance. – PubMed – NCBI CONTEXT: Ocimum basilicum L. (Lamiaceae), popularly known as basil, is part of a group of medicinal plants widely… Read more »

Antioxidant properties of coriander essential oil and linalool and their potential to control Campylobacter spp

Duarte A, Luís A, Oleastro M, Domingues FC Food Control, 2016 ABSTRACT: Foodborne diseases remain common around the world with Campylobacteriosis being the most commonly reported zoonosis in the European Union in 2013. Campylobacter jejuni and Campylobacter coli are the main species associated with human illness. Furthermore, Campylobacter can develop biofilms which is becoming a major… Read more »

Antioxidant activity of linalool in patients with carpal tunnel syndrome

Seol GH, Kang P, Lee HS, Seol GH BMC neurology, 2016 ABSTRACT: BACKGROUND: Carpal tunnel syndrome (CTS) is a common peripheral neuropathy and ischemic-reperfusion injury. Oxidative stress is considered a major cause of CTS. Linalool, a component of essential oils, has antioxidant activity. This study was designed to determine the effects of linalool inhalation on… Read more »

Change in Chemical Composition of Sweet Basil (Ocimum basilicum L.) Essential Oil Caused by Alfalfa mosaic virus

Bruni R, Bellardi MG, Parrella G J Phytopathol, 2015 ABSTRACT: The effects of Alfalfa mosaic virus (AMV) infection on essential oil (EO) content and composition of a Sweet Basil cv. Gigante di Napoli were evaluated. A 10-fold lower extraction yield from infected plants was observed, suggesting that morphological alterations induced by the disease may affect… Read more »

Linalool elicits vasorelaxation of mouse aortae through activation of guanylyl cyclase and K+ channels

Kang P, Seol GH The Journal of pharmacy and pharmacology, 2015 ABSTRACT: OBJECTIVES: The aim of this study was to investigate the cardiovascular relaxing properties of monoterpene alcohol (-)-linalool (LIN), a principal component of several aromatic plants. METHODS: We assessed the effects of LIN on vascular contractility in mouse aortae and evaluated its underlying mechanisms… Read more »

Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer’s mice

Sabogal-Guáqueta AM, Osorio E, Cardona-Gómez GP Neuropharmacology, 2016 ABSTRACT: Alzheimer’s disease (AD) is an age-related progressive neurodegenerative disorder. Several types of treatments have been tested to block or delay the onset of the disease, but none have been completely successful. Diet, lifestyle and natural products are currently the main scientific focuses. Here, we evaluate the… Read more »