Integumentary System

This system includes the skin, hair, sweat glands, and nails. It protects the body against loss of water, abrasion and infection. Common disorders include skin cancer, warts, acne, burns, eczema, vitiligo, and psoriasis.

In vitro antibacterial activity of plant essential oils against Staphylococcus hyicus and Staphylococcus aureus, the causative agents of exudative epidermitis in pigs

Vaillancourt K, Lebel G, Yi L, Grenier D Archives of Microbiology, 2018 ABSTRACT: Greasy pig disease or exudative epidermitis, a generalized or localized skin disease affecting piglets, is mainly caused by Staphylococcus hyicus, although other staphylococcal species such as Staphylococcus aureus may also induce disease. Piglets with skin lesions can be treated systemically with antibiotics…. Read more »

Antimicrobial Essential Oil Combinations to Combat Foot Odour

Orchard A, Viljoen A, van Vuuren SF Planta Medica, 2018 ABSTRACT: Foot odour (bromodosis) is an embarrassing and perplexing condition mostly caused by bacteria of the Brevibacterium species. Essential oils are a credible option as an affordable treatment of odour and contribute towards antimicrobial efficacy. Therefore, this study sets out to investigate the antimicrobial activity… Read more »

The in vitro antimicrobial evaluation of commercially essential oils and their combinations against acne

Orchard A, van Vuuren SF, Viljoen A, Kamatou G International Journal of Cosmetic Science, 2018 ABSTRACT: OBJECTIVE: The study investigated the efficacy of commercial essential oil combinations against the two pathogens responsible for acne with the aim to identify synergy and favourable oils to possibly use in a blend. METHODS AND MATERIALS: Antimicrobial activity was… Read more »

Protective effects of saffron and its active components against oxidative stress and apoptosis in endothelial cells

Rahiman N, Akaberi M, Sahebkar A, Emami SA, Tayarani-Najaran Z Microvascular Research, 2018 ABSTRACT: In this study, we investigated the role of mitogen-activated protein kinase (MAPK) signaling pathways in mediation of the protective effects of saffron extract, saffron essential oil, safranal and crocin on bovine aortic endothelial cells against oxidative injury. The viability of cells… Read more »

Anti-inflammatory, tissue remodeling, immunomodulatory, and anticancer activities of oregano (Origanum vulgare) essential oil in a human skin disease model

Han X, Parker TL Biochimie Open, 2017 ABSTRACT: The use of oregano (Origanum vulgare) essential oil (OEO) has become popular in skin care products. However, scientific research regarding its effects on human skin cells is scarce. In this study, we investigated the biological activity of a commercially available OEO, which is high in carvacrol content,… Read more »

Arborvitae (Thuja plicata) essential oil significantly inhibited critical inflammation- and tissue remodeling-related proteins and genes in human dermal fibroblasts

Han X, Parker TL Biochimie Open, 2017 ABSTRACT: Arborvitae (Thuja plicata) essential oil (AEO) is becoming increasingly popular in skincare, although its biological activity in human skin cells has not been investigated. Therefore, we sought to study AEO’s effect on 17 important protein biomarkers that are closely related to inflammation and tissue remodeling by using… Read more »

Biological activities of frankincense essential oil in human dermal fibroblasts

Han X, Rodriguez D, Parker TL Biochimie Open, 2017 ABSTRACT: Although frankincense essential oil (FREO) has become increasingly popular in skin care, research on its biological activities in human skin cells is scarce, if not completely absent. In the current study, we explored the biological activities of FREO in pre-inflamed human dermal fibroblasts by analyzing… Read more »

Rosemary Essential Oil-Loaded Lipid Nanoparticles: In Vivo Topical Activity from Gel Vehicles

Montenegro L, Pasquinucci L, Zappalà A, Chiechio S, Turnaturi R, Parenti C Pharmaceutics, 2017 ABSTRACT: Although rosemary essential oil (EO) shows many biological activities, its topical benefits have not been clearly demonstrated. In this work, we assessed the effects on skin hydration and elasticity of rosemary EO after topical application via gel vehicles in human volunteers. To… Read more »

Evaluation of antioxidant potential of essential oils of some commonly used Indian spices in in vitro models and in food supplements enriched with omega-6 and omega-3 fatty acids.

Bag A, Chattopadhyay RR Environmental Science and Pollution Research, 2017 ABSTRACT: The aim of this study was to evaluate and compare the antioxidant potential of essential oils of some commonly used Indian spices (black pepper, cinnamon, clove, coriander and cumin) in various in vitro models and in food supplements enriched with omega-6 and omega-3 fatty acids. In… Read more »

Fragrance allergens linalool and limonene allylic hydroperoxides in skin allergy: mechanisms of action focusing on transcription factor Nrf2

Raffalli C, Clouet E, Kuresepi S, Damiens MH, Lepoittevin JP, Pallardy M, Ferret PJ, Giménez-Arnau E, Kerdine-Römer S Toxicology Science, 2017 ABSTRACT: Allergic contact dermatitis (ACD) is regarded as the most frequent expression of immunotoxicity in humans. Many odorant terpenes commonly used in fragrance compositions are considered as weak skin sensitizers, whereas some of their… Read more »