Gandhi GR, Vasconcelos ABS, Haran GH, Calisto VKDS, Jothi G, Quintans JSS, Cuevas LE, Narain N, Júnior LJQ, Cipolotti R, Gurgel RQ Phytomedicine, 2019 ABSTRACT: BACKGROUND: Asthma, the main inflammatory chronic condition affecting the respiratory system, is characterized by hyperresponsiveness and reversible airway obstruction, recruitment of inflammatory cells and excessive production of mucus. Cytokines as… Read more »
Preparation of Peppermint Oil-Based Nanodevices Loaded with Paclitaxel: Cytotoxic and Apoptosis Studies in HeLa Cells
Flores-villaseñor SE, Peralta-rodríguez RD, Padilla-vaca F, Meléndez-ortiz HI, Ramirez-contreras JC, Franco B AAPS PharmSciTech, 2019 ABSTRACT: In this work, several normal, oil-in-water (o/w) microemulsions (MEs) were prepared using peppermint essential oil, jojoba oil, trans-anethole, and vitamin E as oil phases to test their capacity to load paclitaxel (PTX). Initially, pseudo-ternary partial phase diagrams were constructed… Read more »
Essential Oils to Reduce Postoperative Nausea and Vomiting
Fearrington MA, Qualls BW, Carey MG Journal of Perianesthesia Nursing, 2019 ABSTRACT: PURPOSE: The purpose of this study was to determine if using essential oil products for adult patients reduced the need for antiemetics for postoperative nausea and vomiting (PONV). DESIGN: A prospective and retrospective cross-sectional design using a convenience sample. METHODS: Double blinded to… Read more »
Lavender (Lavandula Angustifolia Mill.) Essential Oil Alleviates Neuropathic Pain in Mice With Spared Nerve Injury
Sanna MD, Les F, Lopez V, Galeotti N Frontiers in Pharmacology, 2019 ABSTRACT: Low treatment efficacy represents an important unmet need in neuropathic pain patients and there is an urgent need to develop a more effective pharmacotherapy. An increasing number of patients choose complementary medicine to relieve pain. Lavender essential oil (LEO) is approved by… Read more »
Lemongrass and Cinnamon Bark: Plant Essential Oil Blend as a Spatial Repellent for Mosquitoes in a Field Setting
Peach DAH, Almond M, Gries R, Gries G Journal of Medical Entomology, 2019 ABSTRACT: Plant essential oils (EOs) have been considered as spatial repellents to help disrupt the pathogen transmission cycle of mosquitoes. Our objective was to assess spatial repellency effects of EOs on the tropical yellow fever mosquito, Aedes aegypti (L.) (Diptera: Culicidae) and… Read more »
Antidiabetic Activity of Ajwain Oil in Different In Vitro Models
Aneesa NN, Anitha R, Varghese S Journal of Pharmacy and Bioallied Sciences, 2019 ABSTRACT: CONTEXT: Ajwain oil is an essential oil with thymol as its major constituent which is known for many pharmacological activities. AIMS: To evaluate the anti-hyperglycaemic potential of ajwain oil using different in vitro models. METHODS AND MATERIAL: In vitro α-amylase and… Read more »
Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes
Hakkim FL, Bakshi HA, Khan S, Nasef M, Farzand R, Sam S, Rashan L, Al-Baloshi MS, Abdo Hasson SSA, Jabri AA, McCarron PA, Tambuwala MM Oncotarget, 2019 ABSTRACT: Melanoma is a deadly form of malignancy and according to the World Health Organization 132,000 new cases of melanoma are diagnosed worldwide each year. Surgical resection and… Read more »
Genoprotective Effects of Essential Oil Compounds Against Oxidative and Methylated DNA Damage in Human Colon Cancer Cells
Thapa D, Richardson AJ, Zweifel B, Wallace RJ, Gratz SW Journal of Food Science, 2019 ABSTRACT: Essential oils (EO) are widely used in foods as flavoring and preservative agents. Many of the biological activities of EO have been attributed to major essential oil compounds (EOC) but their direct interaction with colonic epithelial cells and their… Read more »
Essential Oil Compound, Patchouli Alcohol, Represses Tumor Formation in Vivo and Causes G1 Arrest by Downregulating β-catenin Transcriptional Activity in Colon Cancer Cells
Lee J, Lee SH Current Developments in Nutrition, 2019 ABSTRACT: OBJECTIVES: Patchouli alcohol is one of the abundant compounds isolated from essential oil of Pogostemon cablin and shows anti-inflammatory, anti-obese and anti-cancer activities. The current study was designed to investigate if treatment of patchouli alcohol exhibits tumor suppressive activity in colon cancer mouse model and… Read more »
Essential Oils for the Treatment of Herpes Simplex Virus Infections
Schnitzler P Chemotherapy, 2019 ABSTRACT: Infections with herpes simplex virus type (HSV)-1 and HSV-2 are distributed worldwide. Although standard therapies with acyclovir and other synthetic drugs are available, the safety and efficacy of these drugs are limited due to the development of drug resistance and adverse side effects. The literature on essential oils and isolated… Read more »