Essential Oil as a Potential Anti-Acne Topical Nanoemulsion-In Vitro and In Vivo Study

Taleb MH, Abdeltawab NF, Shamma RN, Abdelgayed SS, Mohamed SS, Farag MA, Ramadan MA Molecules, 2018 ABSTRACT: Antibiotics are often prescribed in acne treatment; however, Propionibacterium acnes and Staphylococcus epidermidis, the two of the major acne-associated bacteria, developed antibiotic resistance. Essential oils (EOs) present a natural, safe, efficacious and multifunctional alternative treatment. This study aimed… Read more »

AMPK Activation Mediated by Hinokitiol Inhibits Adipogenic Differentiation of Mesenchymal Stem Cells through Autophagy Flux

Lee JH, Jeong JK, Park SY International Journal of Endocrinology, 2018 ABSTRACT: BACKGROUND AND PURPOSE: Hinokitiol, a natural monopenoid present in the essential oil of Calocedrus formosana heartwood, exerts potent anticancer, anti-inflammatory, antibacterial, and neuroprotective effects on various cells. However, the antiobesity effect of hinokitiol on adipocytes is unclear. EXPERIMENTAL APPROACH: In this study, we… Read more »

Combination of Cloxacillin and Melaleuca armillaris Essential Oil of as an Alternative Against Staphylococcus aureus

Buldain D, Buchamer AV, Marchetti ML, Aliverti F, Bandoni A, Mestorino N Frontiers in Veterinary Science, 2018 ABSTRACT: The emergence of resistance to antibiotics has been favored by abuse in the application of antimicrobials in human and animal medicine. Essential oils are a great resource to deal with this crisis. Melaleuca armillaris belongs to the… Read more »

Volatile Terpenes and Brain Function: Investigation of the Cognitive and Mood Effects of Mentha × Piperita L. Essential Oil with In Vitro Properties Relevant to Central Nervous System Function

Kennedy D, Okello E, Chazot P, Howes MJ, Ohiomokhare S, Jackson P, Haskell-Ramsay C, Khan J, Forster J, Wightman E Nutrients, 2018 ABSTRACT: Extracts of several members of the monoterpene-rich Lamiaceae sub-family Nepetoideae, including those from the Salvia (sage), Melissa (Lemon balm) and Rosmarinus (rosemary) genera, evince cognitive and mood effects in humans that are… Read more »

Antimicrobial activity of essential oils against multidrug-resistant clinical isolates of the Burkholderia cepacia complex

Vasireddy L, Bingle LEH, Davies MS PLoS ONE, 2018 ABSTRACT: Members of the Burkholderia cepacia complex (Bcc) are an important cause of opportunistic or nosocomial infections that may be hard to treat due to a high incidence of multidrug resistance. We characterised a collection of 51 clinical isolates from this complex, assigning them to 18… Read more »

Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials

Rosato A, Carocci A, Catalano A, Clodoveo ML, Franchini C, Corbo F, Carbonara GG, Carrieri A, Fracchiolla G PLoS ONE, 2018 ABSTRACT: Mentha piperita L. essential oil (EO) is employed for external use as antipruritic, astringent, rubefacient and antiseptic. Several studies demonstrated its significant antiviral, antifungal and antibacterial properties. The aim of this work is… Read more »

A Comparative Evaluation of the Cytotoxic and Antioxidant Activity of Mentha crispa Essential Oil, Its Major Constituent Rotundifolone, and Analogues on Human Glioblastoma

Turkez H, Tozlu OO, Lima TC, De brito AEM, De sousa DP Oxidative Medicine and Cellular Longevity, 2018 ABSTRACT: Cancer is a major public health problem around the globe. This disorder is affected by alterations in multiple physiological processes, and oxidative stress has been etiologically implicated in its pathogenesis. Glioblastoma (GBM) is considered the most… Read more »

Investigation of the effect of aromatherapy with Citrus aurantium blossom essential oil on premenstrual syndrome in university students: A clinical trial study

Heydari N, Abootalebi M, Jamalimoghadam N, Kasraeian M, Emamghoreishi M, Akbarzadeh M Complementary Therapies in Clinical Practice, 2018 ABSTRACT: BACKGROUND: The aim was to investigate the effect of aromatherapy using Citrus aurantium blossom essential oil on premenstrual syndrome in university students. METHODS: In this double-blind clinical trial controlled on 62 students from March 2016 to… Read more »

The anticonvulsant and anti-plasmid conjugation potential of Thymus vulgaris chemistry: An in vivo murine and in vitro study

Skalicka-Woźniak K, Walasek M, Aljarba TM, Stapleton P, Gibbons S, Xiao J, Łuszczki JJ Food and Chemical Toxicology, 2018 ABSTRACT: The high-performance counter-current chromatography was used for the efficient purification of single constituents from Thymus vulgaris essential oil. Mixtures of n-heptane, ethyl acetate, methanol, and water (5:2:5:2 and 4:1:4:1 v/v), allowed purification of eugenol, 1-octen-3-… Read more »