Respiratory System

This system includes the trachea, nose, sinuses and lungs. Common disorders can include emphysema, COPD, pneumonia, the flu, the cold, asthma and allergies.

Essential oils and its bioactive compounds modulating cytokines: A systematic review on anti-asthmatic and immunomodulatory properties

Gandhi GR, Vasconcelos ABS, Haran GH, Calisto VKDS, Jothi G, Quintans JSS, Cuevas LE, Narain N, Júnior LJQ, Cipolotti R, Gurgel RQ Phytomedicine, 2019 ABSTRACT: BACKGROUND: Asthma, the main inflammatory chronic condition affecting the respiratory system, is characterized by hyperresponsiveness and reversible airway obstruction, recruitment of inflammatory cells and excessive production of mucus. Cytokines as… Read more »

Protective effect of essential oil from Citrus limon against aspirin-induced toxicity in rats

Bouzenna H, Samout N, Dhibi S, Mbarki S, Akermi S, Khdhiri A, Elfeki A, Hfaiedh N Human & Experimental Toxicology, 2018 ABSTRACT: The present study is planned to examine the antioxidant activity (AA) and the protective effect of the essential oil of Citrus limon (EOC) against aspirin-induced histopathological changes in the brain, lung, and intestine… Read more »

Antibacterial activity of traditional spices against lower respiratory tract pathogens: combinatorial effects of Trachyspermum ammi essential oil with conventional antibiotics

Grădinaru AC, Trifan A, Şpac A, Brebu M, Miron A, Aprotosoaie AC Letters in Applied Microbiology, 2018 ABSTRACT: The aim of this study was to investigate the effects of ajowan essential oil (AjEO)/thymol and antibiotics combinations against three standard strains and six resistant clinical isolates of major respiratory bacteria (Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus… Read more »

Antibacterial activity evaluation of selected essential oils in liquid and vapor phase on respiratory tract pathogens

Ács K, Balázs VL, Kocsis B, Bencsik T, Böszörményi A, Horváth G BMC Complementary and Alternative Medicine, 2018 ABSTRACT: BACKGROUND: The increasing number of multidrug-resistant bacteria and the fact of antibiotic resistance is leading to a continuous need for discovering alternative treatments against infections, e.g. in the case of respiratory tract diseases. Essential oils (EOs),… Read more »

Effect of microencapsulated essential oil form Chamaecyparis obtusa on monocyte-derived dendritic cell activation and CD4+ T cell polarization

Shin SH, Ye MK, Lee DW, Che MH PLoS One, 2018 ABSTRACT: The essential oil of Chamaecyparis obtusa (C. obtusa), which is used in soap, toothpaste, and aromatic agents, has been known to have anti-inflammatory properties. In this study, we investigated the effects of microencapsulated C. obtusa essential oil on airborne fungus-induced dendritic cell (DC)… Read more »

Fennel main constituent, trans‑anethole treatment against LPS‑induced acute lung injury by regulation of Th17/Treg function

Zhang S, Chen X, Devshilt I, Yun Q, Huang C, An L, Dorjbat S, He X Molecular Medicine Reports, 2018 ABSTRACT: Fennel, commonly used in traditional Chinese medicine, is known as Foeniculum vulgare Mill. And its clinical application has been shown to target many biological systems including gastroenterology, endocrinology, gynecology and respiratory. The main constituent… Read more »

Effect of the Lippia alba (Mill.) N.E. Brown essential oil and its main constituents, citral and limonene, on the tracheal smooth muscle of rats

Carvalho PMM, Macêdo CAF, Ribeiro TF, Silva AA, Da Silva RER, de Morais LP, Kerntopf MR, Menezes IRA, Barbosa R Biotechnology Reports, 2017 ABSTRACT: The Lippia alba (Mill.) N.E. Brown (Verbenaceae) species, has effects sedative, analgesic and spasmolytic properties. This study had as its main objective to evaluate the essential oil of L. alba (EOLa)… Read more »

Relaxant effect of Lippia origanoides essential oil in guinea-pig trachea smooth muscle involves potassium channels and soluble guanylyl cyclase

Menezes PMN, Brito MC, Paiva GO, Santos COD, Oliveira LM, Ribeiro LAA, Lima JT, Lucchese AM, Silva FS Journal of Ethnopharmacology, 2018 ABSTRACT: ETHNOPHARMACOLOGICAL RELEVANCE: Lippia origanoides H.B.K. is an aromatic species used in folk medicine to treat respiratory diseases, including asthma. AIM OF THE STUDY: The aim of this work was to evaluate the… Read more »

Lemongrass essential oil and citral inhibit Src/Stat3 activity and suppress the proliferation/survival of small-cell lung cancer cells, alone or in combination with chemotherapeutic agents

Maruoka T, Kitanaka A, Kubota Y, Yamaoka G, Kameda T, Imataki O, Dobashi H, Bandoh S, Kadowaki N, Tanaka T International Journal of Oncology, 2018 ABSTRACT: Small-cell lung cancer (SCLC) is intractable due to its high propensity for relapse. Novel agents are thus needed for SCLC treatment. Lemongrass essential oil (LG-EO) and its major constituent,… Read more »

Alcoholic monoterpenes found in essential oil of aromatic spices reduce allergic inflammation by the modulation of inflammatory cytokines

Pina LTS, Ferro JNS, Rabelo TK, Oliveira MA, Scotti L, Scotti MT, Walker CIB, Barreto EO, Quintans Júnior LJ, Guimarães AG Natural Product Research, 2018 ABSTRACT: Allergic inflammation is a response of the body against pathogens by cytokine release and leucocyte recruitment. Recently, there was an increase in morbimortality associated with allergic inflammation, especially asthma…. Read more »