Gastrointestinal motility enhancing effect of ginger and its active constituents

Yamahara J, Huang QR, Li YH, Xu L, Fujimura H
Chemical and Pharmaceutical Bulletin, 1990


ABSTRACT:

The effect of ginger root (Zingiberis Rhizoma) on gastrointestinal motility was examined based on its ability to enhance charcoal meal transport in mice. Oral administrations of the acetone extract of ginger (which contains volatile oils and bitter substances) at 75 mg/kg, [6]-shogaol at 2.5 mg/kg, or a [6]-, [8]- or [10]-gingerol at 5 mg/kg enhanced the transport of a charcoal meal. The effects of these substances were similar to or slightly weaker than those of metoclopramide and donperidone.

CITATION:

Yamahara J, Huang QR, Li YH, Et Al. Gastrointestinal motility enhancing effect of ginger and its active constituents. Chem Pharm Bull (Tokyo). 1990;38(2):430-431.


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