Okazaki K, Kawazoe K, Takaishi Y
Phytotheraphy Research, 2002
Two antiaggregant compounds, thymol (compound 1) and 3,4,3′,4′-tetrahydroxy-5,5′-diisopropyl-2,2′-dimethylbiphenyl (compound 2) were isolated from the leaves of thyme (Thymus vulgaris L.). The structures were determined by (1)H-, (13)C-NMR and mass spectra (MS) studies. These compounds inhibited platelet aggregation induced by collagen, ADP, arachidonic acid (AA) and thrombin except that compound 2 did not inhibit platelet aggregation induced by thrombin.
Okazaki K, Kawazoe K, Takaishi Y. Human Platelet Aggregation Inhibitors from Thyme (Thymus vulgaris L.). Phytother Res. 2002;16(4):398-399.