Search Results for: cancer

Anti-inflammatory, tissue remodeling, immunomodulatory, and anticancer activities of oregano (Origanum vulgare) essential oil in a human skin disease model

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Han X, Parker TL Biochimie Open, 2017 ABSTRACT: The use of oregano (Origanum vulgare) essential oil (OEO) has become popular in skin care products. However, scientific research regarding its effects on human skin cells is scarce. In this study, we investigated the biological activity of a commercially available OEO, which is high in carvacrol content,… Read more »

Preclinical development and clinical use of perillyl alcohol for chemoprevention and cancer therapy

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Chen TC, Fonseca CO, Schönthal AH American Journal of Cancer Research, 2015 ABSTRACT: Perillyl alcohol (POH) is a naturally occurring dietary monoterpene isolated from the essential oils of lavender, peppermint, and other plants. Medical interest in this compound was generated by research findings showing that POH was able to inhibit the growth of tumor cells… Read more »

Essential oils and their constituents as anticancer agents: a mechanistic view

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Gautam N, Mantha AK, Mittal S BioMed Research International, 2014 ABSTRACT: Exploring natural plant products as an option to find new chemical entities as anticancer agents is one of the fastest growing areas of research. Recently, in the last decade, essential oils (EOs) have been under study for their use in cancer therapy and the… Read more »

Composition of Volatile Oil and Methanolic Extract of Jordanian Melissa Officinals L. and Actions Againsthuman Cancer Cell Lines

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Barakat SA, Hudaib M, EL-asadand N, Burns DT Oriental Journal of Chemistry, 2016 ABSTRACT: The essential oil of Jordanian  Melissa officinalis L. were obtained by hydro-distillation and analyzed by Gas Chromatography – Mass Spectrometry. Components representing 96.40%  of the total oil were identified. The methanolic extract and the volatile oil of Melissa officinalisL, were tested… Read more »

Ligands for cannabinoid receptors, promising anticancer agents

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Nikan M, Nabavi SM, Manayi A Life Sciences, 2016 ABSTRACT: Cannabinoid compounds are unique to cannabis and provide some interesting biological properties. These compounds along with endocannabinoids, a group of neuromodulator compounds in the body especially in brain, express their effects by activation of G-protein-coupled cannabinoid receptors, CB1 and CB2. There are several physiological properties… Read more »

Furanodiene enhances the anti-cancer effects of doxorubicin on ERα-negative breast cancer cells in vitro

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Zhong ZF, Qiang WA, Wang CM, Tan W, Wang YT European journal of pharmacology, 2016 ABSTRACT: Furanodiene is a natural product isolated from Rhizoma curcumae, and exhibits broad-spectrum anti-cancer activities in vitro and in vivo. Our previous study proved that furanodiene could increase growth inhibition of steroidal agent in ERα-positive breast cancer cells, but whether… Read more »

β-Bisabolene, a Sesquiterpene from the Essential Oil Extract of Opoponax (Commiphora guidottii), Exhibits Cytotoxicity in Breast Cancer Cell Lines

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Yeo SK, Ali AY, Hayward OA, Turnham D, Jackson T, Bowen ID, Clarkson R Phytotherapy research : PTR, 2016 ABSTRACT: The essential oils from Commiphora species have for centuries been recognized to possess medicinal properties. Here, we performed gas chromatography-mass spectrometry on the essential oil from opoponax (Commiphora guidotti) and identified bisabolene isomers as the… Read more »

α- and β-Santalols Directly Interact with Tubulin and Cause Mitotic Arrest and Cytotoxicity in Oral Cancer Cells

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Lee B, Bohmann J, Reeves T, Levenson C, Risinger AL Journal of natural products, 2015 ABSTRACT: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, with no major advancements in treatment over the past 40 years. The current study explores the biological effects of East Indian sandalwood oil (EISO) and… Read more »