Capasso R, Pinto L, Vuotto ML, Di Carlo G
This study examines the anti-ulcerogenic activity of eugenol, a natural compound obtained from many natural sources. Gastric ulcers, induced by administration of two ulcerogenic agents, i.e. platelet activating factor (PAF) and ethanol, were dose-dependently and significantly reduced by eugenol (10-100 mg/kg, p.o.) pre-treatment. Eugenol was able to reduce not only the number of ulcers but also the gravity of lesions.
Capasso R, Pinto L, Vuotto ML, Et Al. Preventive effect of eugenol on PAF and ethanol-induced gastric mucosal damage. Fitoterapia. 2000;71 Suppl 1:S131-137.