Preventive effect of eugenol on PAF and ethanol-induced gastric mucosal damage

Capasso R, Pinto L, Vuotto ML, Di Carlo G
Fitoterapia, 2000


ABSTRACT:

This study examines the anti-ulcerogenic activity of eugenol, a natural compound obtained from many natural sources. Gastric ulcers, induced by administration of two ulcerogenic agents, i.e. platelet activating factor (PAF) and ethanol, were dose-dependently and significantly reduced by eugenol (10-100 mg/kg, p.o.) pre-treatment. Eugenol was able to reduce not only the number of ulcers but also the gravity of lesions.

CITATION:

Capasso R, Pinto L, Vuotto ML, Et Al. Preventive effect of eugenol on PAF and ethanol-induced gastric mucosal damage. Fitoterapia. 2000;71 Suppl 1:S131-137.


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