Gao Y, Pemberton CC, Zhang Y, Weber PM The journal of chemical physics, 2016 ABSTRACT: The ultrafast relaxation pathway of α-terpinene was studied by photoionization-photoelectron spectroscopy for a range of excitation conditions. Time-resolved spectra were obtained upon optical excitation with ultrashort laser pulses at 5.56 eV, 4.96 eV, 4.76 eV, and 4.56 eV, followed by… Read more »
Oregano Essential Oil Improves Intestinal Morphology and Expression of Tight Junction Proteins Associated with Modulation of Selected Intestinal Bacteria and Immune Status in a Pig Model
Yi Zou, Quanhang Xiang, Jun Wang, Jian Peng, Hongkui Wei BioMed Research International, 2016 ABSTRACT: Oregano essential oil (OEO) has long been used to improve the health of animals, particularly the health of intestine, which is generally attributed to its antimicrobial and anti-inflammatory effects. However, how OEO acts in the intestine of pig is still… Read more »
Identification and analysis of miRNAs and their targets in ginger using bioinformatics approach
Singh N, Srivastava S, Sharma A Gene, 2015 ABSTRACT: MicroRNAs (miRNAs) are a large family of endogenous small RNAs derived from the non-protein coding genes. miRNA regulates the gene expression at the post-transcriptional level and plays an important role in plant development. Zingiber officinale is an important medicinal plant having numerous therapeutic properties. Its bioactive… Read more »
Cytotoxicity and genotoxicity of zingiberene on different neuron cell lines in vitro
Togar B, Turkez H, Tatar A, Hacimuftuoglu A, Geyikoglu F Cytotechnology, 2015 ABSTRACT: The main objective of this study is to investigate the cytotoxic, genotoxic and antioxidant properties of zingiberene (ZBN) in an in vitro rat brain cell culture study. The cytotoxic effect was determined against the rat neuron and N2a neuroblastoma (N2a-NB) cell lines… Read more »
Biphasic cardiovascular and respiratory effects induced by β-citronellol
Ribeiro-Filho HV, de Souza Silva CM, de Siqueira RJ, Lahlou S, Dos Santos AA, Magalhães PJ European journal of pharmacology, 2016 ABSTRACT: β-Citronellol is a monoterpene found in the essential oil of various plants with antihypertensive properties. In fact, β-citronellol possesses hypotensive actions due to its vasodilator abilities. Here we aimed to show that β-citronellol… Read more »
Cinnamaldehyde modulates LPS-induced systemic inflammatory response syndrome through TRPA1-dependent and independent mechanisms
Mendes SJ, Sousa FI, Pereira DM, Ferro TA, Pereira IC, Silva BL, Pinheiro AJ, Mouchrek AQ, Monteiro-Neto V, Costa SK, Nascimento JL, Grisotto MA, da Costa R, Fernandes ES International immunopharmacology, 2016 ABSTRACT: Cinnamaldehyde is a natural essential oil suggested to possess anti-bacterial and anti-inflammatory properties; and to activate transient receptor potential ankyrin 1 (TRPA1)… Read more »
Dietary Geraniol by Oral or Enema Administration Strongly Reduces Dysbiosis and Systemic Inflammation in Dextran Sulfate Sodium-Treated Mice
Luigia De Fazio, Enzo Spisni, Elena Cavazza, Antonio Strillacci, Marco Candela, Manuela Centanni, Chiara Ricci, Fernando Rizzello, Massimo Campieri, Maria C. Valerii Frontiers in pharmacology, 2016 ABSTRACT: (Trans)-3,7-Dimethyl-2,6-octadien-1-ol, commonly called geraniol (Ge-OH), is an acyclic monoterpene alcohol with well-known anti-inflammatory, antitumoral, and antimicrobial properties. It is widely used as a preservative in the food industry… Read more »
Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer’s mice
Sabogal-Guáqueta AM, Osorio E, Cardona-Gómez GP Neuropharmacology, 2016 ABSTRACT: Alzheimer’s disease (AD) is an age-related progressive neurodegenerative disorder. Several types of treatments have been tested to block or delay the onset of the disease, but none have been completely successful. Diet, lifestyle and natural products are currently the main scientific focuses. Here, we evaluate the… Read more »
Effects of monoterpenes on ion channels of excitable cells
Oz M, Lozon Y, Sultan A, Yang KH, Galadari S Pharmacology & therapeutics, 2015 ABSTRACT: Monoterpenes are a structurally diverse group of phytochemicals and a major constituent of plant-derived ‘essential oils’. Monoterpenes such as menthol, carvacrol, and eugenol have been utilized for therapeutical purposes and food additives for centuries and have been reported to have… Read more »
Hepatoprotective effect of Commiphora myrrha against d-GalN/LPS-induced hepatic injury in a rat model through attenuation of pro inflammatory cytokines and related genes
Ahmad A, Raish M, Ganaie MA, Ahmad SR, Mohsin K, Al-Jenoobi FI, Al-Mohizea AM, Alkharfy KM
Pharmaceutical Biology, 2015