In Vitro Studies on Ameliorative Effects of Limonene on Cadmium-Induced Genotoxicity in Cultured Human Peripheral Blood Lymphocytes

Verma N, Yadav A, Bal S, Gupta R, Aggarwal N Applied Biochemistry and Biotechnology, 2018 ABSTRACT: Cadmium (Cd) is a non-redox metal that can indirectly cause oxidative stress by depleting cellular levels of glutathione. It is well-known for the generating reactive oxygen species (ROS) such as hydroxyl radicals, superoxide anions, nitric oxide, and hydrogen peroxide…. Read more »

Functional Oil from Black Seed Differentially Inhibits Aldose-reductase and Ectonucleotidase Activities by Up-regulating Cellular Energy in Haloperidol-induced Hepatic Toxicity in Rat Liver

Kehinde AJ Journal of Oleo Science, 2017 ABSTRACT: In this study, the effect of rate-limiting enzymes involved in degradation of hepatic adenosine and intracellular sorbitol was investigated in rats exposed to haloperidol (HAL) and treated with functional oil (FO), containing principal active phytochemicals from black seed. Animals were divided into six groups (n=10): Distilled water,… Read more »