Copaiba oil: chemical composition and influence on in vitro cutaneous permeability of Celecoxib.

Quiñones OG, Abranches RP, Nakamura MJ, de Souza Ramos MF, Pierre MBR Current Drug Delivery, 2017 BACKGROUND: Use of topical or transdermal administration of Celecoxib (Cxb) is an interesting strategy in cutaneous treatments since it reduces or avoids side effects of the oral route. However, Cxb´s high lipophilicity and the stratum corneum (SC) barrier impair… Read more »