Could beta-myrcene be an alternative to albendazole for the treatment of experimental cystic echinococcosis

Fabbri J, Maggiore MA, Pensel PE, Albani CM, Denegri GM, Elissondo MC Acta Tropica, 2018 ABSTRACT: Echinococcus granulosus causes hydatidosis or cystic echinococcosis in humans and livestock. In humans, this disease can be managed with surgery, percutaneous treatment, chemotherapy and/or observation. The chemotherapeutic agents used and approved for treatment of hydatidosis are benzimidazoles. Because of… Read more »

In vitro Protoscolicidal Effects of Cinnamomum zeylanicum Essential Oil and Its Toxicity in Mice

Mahmoudvand H, Mahmoudvand H, Oliaee RT, Kareshk AT, Mirbadie SR, Aflatoonian MR Pharmacognosy Magazine, 2017 BACKGROUND: This study investigates the scolicidal effects of Cinnamomum zeylanicum essential oilagainst the protoscoleces of hydatid cysts and its toxicity in the mice model. MATERIALS AND METHODS: Gas chromatography/mass spectroscopy analyses were used to identify the constituents of essential oil. Protoscoleces were treated… Read more »