A Comparative Evaluation of the Cytotoxic and Antioxidant Activity of Mentha crispa Essential Oil, Its Major Constituent Rotundifolone, and Analogues on Human Glioblastoma

Turkez H, Tozlu OO, Lima TC, De brito AEM, De sousa DP Oxidative Medicine and Cellular Longevity, 2018 ABSTRACT: Cancer is a major public health problem around the globe. This disorder is affected by alterations in multiple physiological processes, and oxidative stress has been etiologically implicated in its pathogenesis. Glioblastoma (GBM) is considered the most… Read more »

Human Adenocarcinoma Cell Line Sensitivity to Essential Oil Phytocomplexes from Pistacia Species: a Multivariate Approach

Buriani A, Fortinguerra S, Sorrenti V, Dall’Acqua S, Innocenti G, Montopoli M, Gabbia D, Carrara M Molecules, 2017 ABSTRACT: Principal component analysis (PCA) multivariate analysis was applied to study the cytotoxic activity of essential oils from various species of the Pistacia genus on human tumor cell lines. In particular, the cytotoxic activity of essential oils obtained from P…. Read more »

Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral

Adukwu EC, Bowles M, Edwards-Jones V, Bone H Applied microbiology and biotechnology, 2016 ABSTRACT: The aim of this study was to determine the antimicrobial effects of lemongrass essential oil (C. flexuosus) and to determine cytotoxic effects of both test compounds on human dermal fibroblasts. Antimicrobial susceptibility screening was carried out using the disk diffusion method…. Read more »

Chemical composition and in vitro evaluation of antioxidant, antimicrobial, cytotoxicity and anti-acetylcholinesterase properties of Tunisian Origanum majorana L. essential oil

Hajlaoui H, Mighri H, Aouni M, Gharsallah N, Kadri A Microbial pathogenesis, 2016 ABSTRACT: This study investigated the chemical composition and evaluated the antioxidant, antimicrobial, cytotoxic and anti-acetylcholinesterase properties of Tunisian Origanum majorana essential oil. The findings showed that the oil exhibited high activity, particularly in terms of reducing power and β-Carotene bleaching, inducing higher… Read more »

Cytotoxicity and genotoxicity of zingiberene on different neuron cell lines in vitro

Togar B, Turkez H, Tatar A, Hacimuftuoglu A, Geyikoglu F Cytotechnology, 2015 ABSTRACT: The main objective of this study is to investigate the cytotoxic, genotoxic and antioxidant properties of zingiberene (ZBN) in an in vitro rat brain cell culture study. The cytotoxic effect was determined against the rat neuron and N2a neuroblastoma (N2a-NB) cell lines… Read more »

β-Bisabolene, a Sesquiterpene from the Essential Oil Extract of Opoponax (Commiphora guidottii), Exhibits Cytotoxicity in Breast Cancer Cell Lines

Yeo SK, Ali AY, Hayward OA, Turnham D, Jackson T, Bowen ID, Clarkson R Phytotherapy research : PTR, 2016 ABSTRACT: The essential oils from Commiphora species have for centuries been recognized to possess medicinal properties. Here, we performed gas chromatography-mass spectrometry on the essential oil from opoponax (Commiphora guidotti) and identified bisabolene isomers as the… Read more »