Preparation of Peppermint Oil-Based Nanodevices Loaded with Paclitaxel: Cytotoxic and Apoptosis Studies in HeLa Cells

Flores-villaseñor SE, Peralta-rodríguez RD, Padilla-vaca F, Meléndez-ortiz HI, Ramirez-contreras JC, Franco B AAPS PharmSciTech, 2019 ABSTRACT: In this work, several normal, oil-in-water (o/w) microemulsions (MEs) were prepared using peppermint essential oil, jojoba oil, trans-anethole, and vitamin E as oil phases to test their capacity to load paclitaxel (PTX). Initially, pseudo-ternary partial phase diagrams were constructed… Read more »

Genoprotective Effects of Essential Oil Compounds Against Oxidative and Methylated DNA Damage in Human Colon Cancer Cells

Thapa D, Richardson AJ, Zweifel B, Wallace RJ, Gratz SW Journal of Food Science, 2019 ABSTRACT: Essential oils (EO) are widely used in foods as flavoring and preservative agents. Many of the biological activities of EO have been attributed to major essential oil compounds (EOC) but their direct interaction with colonic epithelial cells and their… Read more »

In Vitro Effect of Cinnamomum zeylanicum Blume Essential Oil on Candida spp. Involved in Oral Infections

Rangel ML, De aquino SG, De lima JM, Castellano LR, De castro RD Evidence Based Complementary and Alternative Medicine, 2018 ABSTRACT: The present study demonstrates the antifungal potential of chemically characterized essential oil (EO) of Cinnamomum zeylanicum Blume on Candida spp. biofilm and establishes its mode of action, effect on fungal growth kinetics, and cytotoxicity… Read more »

Chemical Composition, Cytotoxic, Apoptotic and Antioxidant Activities of Main Commercial Essential Oils in Palestine: A Comparative Study

A Al-Tamimi M, Rastall B, M Abu-Reidah I Medicines (Basel), 2016 ABSTRACT: Background: Essential oils (EOs) are complex mixtures of several components gifted with a wide array of biological activities. The present research was designed to evaluate whether commercial essential oils could be effective by examining their in vitro antioxidant, cytotoxic, and apoptotic properties of nine commercially available EOs… Read more »

Cytotoxicity of the Essential Oil of Fennel (Foeniculum vulgare) from Tajikistan

Sharopov F, Valiev A, Satyal P, Gulmurodov I, Yusufi S, Setzer WN, Wink M Foods, 2017 ABSTRACT: The essential oil of fennel (Foeniculum vulgare) is rich in lipophilic secondary metabolites, which can easily cross cell membranes by free diffusion. Several constituents of the oil carry reactive carbonyl groups in their ring structures. Carbonyl groups can… Read more »

Chemical composition and evaluation of the antibacterial and Cytotoxic activities of the essential oil from the leaves of Myracrodruon urundeuva

Rebouças de Araújo ÍD, Coriolano de Aquino N, Véras de Aguiar Guerra AC, Ferreira de Almeida Júnior R, Mendonça Araújo R, Fernandes de Araújo Júnior R, Silva Farias KJ, Fernandes JV, Sousa Andrade V BioMed Central Complementary and Alternative Medicine, 2017 BACKGROUND: This study evaluated the in vitro activity of essential oil extracted from the leaves of… Read more »