The anticonvulsant and anti-plasmid conjugation potential of Thymus vulgaris chemistry: An in vivo murine and in vitro study

Skalicka-Woźniak K, Walasek M, Aljarba TM, Stapleton P, Gibbons S, Xiao J, Łuszczki JJ Food and Chemical Toxicology, 2018 ABSTRACT: The high-performance counter-current chromatography was used for the efficient purification of single constituents from Thymus vulgaris essential oil. Mixtures of n-heptane, ethyl acetate, methanol, and water (5:2:5:2 and 4:1:4:1 v/v), allowed purification of eugenol, 1-octen-3-… Read more »

Transcriptomic approach and membrane fatty acid analysis to study the response mechanisms of Escherichia coli to thyme essential oil, carvacrol, 2-(E)-hexanal and citral exposure

Siroli L, Braschi G, De jong A, Kok J, Patrignani F, Lanciotti R Journal of Applied Microbiology, 2018 ABSTRACT: AIMS: The application of essential oils (EOs) and their components as food preservatives is promising but requires a deeper understanding of their mechanisms of action. This study aims to evaluate the effects of thyme EO, carvacrol,… Read more »

Antimicrobial Activity of Five Essential Oils against Bacteria and Fungi Responsible for Urinary Tract Infections

Ebani VV, Nardoni S, Bertelloni F, Pistelli L, Mancianti F Molecules, 2018 ABSTRACT: Urinary tract infections are frequently encountered in small animal practice. Escherichia coli and Enterococcus spp. are the most common agents associated to these infections, even though other bacteria and yeasts, such as Candida albicans and Candida famata, may be involved. In view… Read more »

Structure-activity modelling of essential oils, their components, and key molecular parameters and descriptors

Owen L, Laird K, Wilson PB Molecular and Cellular Probes, 2017 ABSTRACT: Many essential oil components are known to possess broad spectrum antimicrobial activity, including against antibiotic resistant bacteria. These compounds may be a useful source of new and novel antimicrobials. However, there is limited research on the structure-activity relationship (SAR) of essential oil compounds,… Read more »

Critical synergistic concentration of lecithin phospholipids improve the antimicrobial activity of eugenol against Escherichia coli

Zhang H, Dudley EG, Harte F Applied Environmental Microbiology, 2017 ABSTRACT: In this study, the effect of individual lecithin phospholipids on the antimicrobial properties of eugenol against E. coli C600 was investigated. We tested five major phospholipids common in soy or egg lecithin (DPPC, DSPC, DPPE, DPPA and DPPS) and one synthetic cationic phospholipid (EPC 18:0). Among six phospholipids,… Read more »

The role of structure and molecular properties of terpenoids in determining their antimicrobial activity

Griffin SG, Wyllie SG, Julie L, Markham, Leach DN Flavour and Fragrance Journal, 1999 ABSTRACT: The minimum inhibitory concentrations (MIC) of 60 terpenoids against Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Candida albicans have been determined. Hierarchical cluster analysis was used to group the compounds into five groups according to their activity patterns against the four microorganisms. K-Means… Read more »

Oregano Essential Oil Improves Intestinal Morphology and Expression of Tight Junction Proteins Associated with Modulation of Selected Intestinal Bacteria and Immune Status in a Pig Model

Yi Zou, Quanhang Xiang, Jun Wang, Jian Peng, Hongkui Wei BioMed Research International, 2016 ABSTRACT: Oregano essential oil (OEO) has long been used to improve the health of animals, particularly the health of intestine, which is generally attributed to its antimicrobial and anti-inflammatory effects. However, how OEO acts in the intestine of pig is still… Read more »

Antioxidant properties of coriander essential oil and linalool and their potential to control Campylobacter spp

Duarte A, Luís A, Oleastro M, Domingues FC Food Control, 2016 ABSTRACT: Foodborne diseases remain common around the world with Campylobacteriosis being the most commonly reported zoonosis in the European Union in 2013. Campylobacter jejuni and Campylobacter coli are the main species associated with human illness. Furthermore, Campylobacter can develop biofilms which is becoming a major… Read more »