The antifungal activity of essential oil from Melaleuca leucadendra (L.) L. grown in China and its synergistic effects with conventional antibiotics against Candida

Zhang J, Wu H, Jiang D, Yang Y, Tang W, Xu K Natural Product Research, 2018 ABSTRACT: To identify the natural antifungal agents, the antifungal activities of Melaleuca leucadendra (L.) L. essential oil (ML-EO) from Fujian Province of China were assayed. Treatment of ML-EO in combination with the front-line using antibiotics against Candida led to… Read more »

Anti-inflammatory and anti-edematogenic action of the Croton campestris A. St.-Hil (Euphorbiaceae) essential oil and the compound β-caryophyllene in in vivo models

Oliveira-Tintino CDM, Pessoa RT, Fernandes MNM, Alcântara IS, da Silva BAF, de Oliveira MRC, Martins AOBPB, da Silva MDS, Tintino SR, Rodrigues FFG, da Costa JGM, de Lima SG, Kerntopf MR, da Silva TG, de Menezes IRA Phytomedicine: International Journal of Phytotherapy and Phytopharmacology, 2018 ABSTRACT: BACKGROUND: Inflammation makes up a set of vascularized tissue… Read more »

Combination of essential oil and ciprofloxacin to inhibit/eradicate biofilms in multidrug-resistant Klebsiella pneumoniae

Mohamed SH, Mohamed MSM, Khalil MS, Azmy M, Mabrouk MI Journal of Applied Microbiology, 2018 ABSTRACT: AIM: This study aimed to test biofilm inhibition activities of each of essential oils (EOs), main compounds of EOs and enzymes against pathogenic Klebsiella pneumonia. METHODS AND RESULTS: Effect of seven EOs and three enzymes was tested on formation… Read more »

Cymbopogon citratus and Cymbopogon giganteus essential oils have cytotoxic effects on tumor cell cultures. Identification of citral as a new putative anti-proliferative molecule

Bayala B, Bassole IHN, Maqdasy S, Baron S, Simpore J, Lobaccaro JA Biochimie, 2018 ABSTRACT: Cymbopogon species are used as traditional remedies in Burkina Faso for treating several diseases. We aimed to study the effects of their essential oils on cancer cell lines. For that purpose, Cymbopogon citratus (DC.) Stapf. and Cymbopogon giganteus Chiov. were… Read more »

Cinnamomum zeylanicum bark essential oil induces cell wall remodelling and spindle defects in Candida albicans

Shahina Z, El-Ganiny AM, Minion J, Whiteway M, Sultana T, Dahms TES Fungal Biology and Biotechnology, 2018 ABSTRACT: BACKGROUND: Cinnamon (Cinnamomum zeylanicum) bark extract exhibits potent inhibitory activity against Candida albicans but the antifungal mechanisms of this essential oil remain largely unexplored. RESULTS: We analyzed the impact of cinnamon bark oil on C. albicans RSY150,… Read more »

Selected terpenes from leaves of Ocimum basilicum L. induce hemoglobin accumulation in human K562 cells

Giordana F, Nicola M, Valentina C, Torricelli P, Beninati S, Tagliati F, Mischiati C Fitoterapia, 2018 ABSTRACT: Re-expression of fetal hemoglobin (HbF) was proposed as a possible therapeutic strategy for β-haemoglobinopathies. Although several inducers of HbF were tested in clinical trials, only hydroxyurea (HU) received FDA approval. Despite it produced adequate HbF levels only in… Read more »

Aromatherapy massage with lavender essential oil and the prevention of disability in ADL in patients with osteoarthritis of the knee: A randomized controlled clinical trial

Nasiri A, Mahmodi MA Complimentary Therapies in Clinical Practice, 2018 ABSTRACT: BACKGROUND: Knee osteoarthritis is considered as one of the most prevalent musculoskeletal disorders which leads to joint degeneration and consequently disability in activities of daily living. This study aimed to evaluate the effects of aromatherapy massage with lavender essence on activities of daily living… Read more »

Involvement of Bax and Bcl-2 in Induction of Apoptosis by Essential Oils of Three Lebanese Salvia Species in Human Prostate Cancer Cells

Russo A, Cardile V, Graziano ACE, Avola R, Bruno M, Rigano D International Journal of Molecular Sciences, 2018 ABSTRACT: Prostate cancer is one of the most common forms of cancer in men, and research to find more effective and less toxic drugs has become necessary. In the frame of our ongoing program on traditionally used… Read more »

Protective effects of Mentha piperita L. leaf essential oil against CCl4 induced hepatic oxidative damage and renal failure in rats

Bellassoued K, Ben Hsouna A, Athmouni K, van Pelt J, Makni Ayadi F, Rebai T, Elfeki A Lipids in Health and Disease, 2018 ABSTRACT: BACKGROUND: Mentha piperita L. is a flowering plant belonging to the Lamiaceae family. Mentha plants constitute one of the main valuable sources of essential oil used in foods and for medicinal… Read more »

A novel approach of substitution therapy with inhalation of essential oil for the reduction of inhalant craving: A double-blinded randomized controlled trial

Kalayasiri R, Maneesang W, Maes M Psychiatry Research, 2018 ABSTRACT: Inhalants, which are neurotoxic central nervous system (CNS) suppressants, are frequently abused by young adults. Unlike other CNS depressants, including alcohol and opiates, no treatment is currently approved for inhalant dependence. In this report, a novel approach of substitution treatment for inhalant addiction was explored… Read more »