A Comparative Evaluation of the Cytotoxic and Antioxidant Activity of Mentha crispa Essential Oil, Its Major Constituent Rotundifolone, and Analogues on Human Glioblastoma

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Turkez H, Tozlu OO, Lima TC, De brito AEM, De sousa DP Oxidative Medicine and Cellular Longevity, 2018 ABSTRACT: Cancer is a major public health problem around the globe. This disorder is affected by alterations in multiple physiological processes, and oxidative stress has been etiologically implicated in its pathogenesis. Glioblastoma (GBM) is considered the most… Read more »

Thymoquinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells

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Gurung RL, Lim SN, Khaw AK, Soon JF, Shenoy K, Mohamed Ali S, Jayapal M, Sethu S, Baskar R, Hande MP PloS One, 2010 ABSTRACT: BACKGROUND: A major concern of cancer chemotherapy is the side effects caused by the non-specific targeting of both normal and cancerous cells by therapeutic drugs. Much emphasis has been placed on discovering new compounds that target tumour cells more… Read more »