Selected terpenes from leaves of Ocimum basilicum L. induce hemoglobin accumulation in human K562 cells

Giordana F, Nicola M, Valentina C, Torricelli P, Beninati S, Tagliati F, Mischiati C Fitoterapia, 2018 ABSTRACT: Re-expression of fetal hemoglobin (HbF) was proposed as a possible therapeutic strategy for β-haemoglobinopathies. Although several inducers of HbF were tested in clinical trials, only hydroxyurea (HU) received FDA approval. Despite it produced adequate HbF levels only in… Read more »