Essential oil of lavender in anxiety disorders: Ready for prime time?

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Malcolm BJ, Tallian K The Mental Health Clinician, 2018 ABSTRACT: Anxiety disorders are some of the most common psychiatric disorders, with potentially debilitating consequences on individual function. Existing pharmacotherapies for anxiety disorders are limited by delay to therapeutic effect, dependence, tolerance, withdrawal, and abuse potential. Therefore, safe and evidence-based complementary or alternative therapies may be… Read more »

Anti-inflammatory effect of essential oil from Citrus aurantium L. var. amara Engl

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Shen CY, Jiang JG, Ou-Yang Q, Zhu W Journal of Agricultural and Food Chemistry, 2017 ABSTRACT: Essential oil has been popularly used as an alternative for the treatment of inflammation. The bioactivities of essential oil from blossoms of Citrus aurantium L. var. amara Engl (CAVAO) showed greater anti-inflammation potential than that of antioxidant, anticancer, and 3T3-L1 proliferation inhibition…. Read more »

Metabolic Products of Linalool and Modulation of GABAA Receptors

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Milanos S, Elsharif SA, Janzen D, Buettner A, Villmann C Frontiers in Chemistry, 2017 ABSTRACT: Terpenoids are major subcomponents in aroma substances which harbor sedative physiological potential. We have demonstrated that various monoterpenoids such as the acyclic linalool enhance GABAergic currents in an allosteric manner in vitro upon overexpression of inhibitory α1β2 GABAA receptors in various expression systems. However, in plants or humans, i.e.,… Read more »

Linalyl acetate as a major ingredient of lavender essential oil relaxes the rabbit vascular smooth muscle through dephosphorylation of myosin light chain

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Koto R, Imamura M, Watanabe C, Obayashi S, Shiraishi M, Sasaki Y, Azuma H Journal of cardiovascular pharmacology, 2006 ABSTRACT: In a preliminary experiment, we found that lavender essential oil relaxes vascular smooth muscle. Thus, the present experiments were designed to investigate the relaxation mechanism of linalyl acetate as the major ingredient of lavender essential… Read more »

Unraveling the Rat Intestine, Spleen and Liver Genome-Wide Transcriptome after the Oral Administration of Lavender Oil by a Two-Color Dye-Swap DNA Microarray Approach

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Kubo H, Shibato J, Saito T, Ogawa T, Rakwal R, Shioda S PloS one, 2015 ABSTRACT: The use of lavender oil (LO)–a commonly, used oil in aromatherapy, with well-defined volatile components linalool and linalyl acetate–in non-traditional medicine is increasing globally. To understand and demonstrate the potential positive effects of LO on the body, we have… Read more »