Han X, Beaumont C, Rodriguez D, Bahr T Phytotherapy Research, 2018 ABSTRACT: Very few studies have investigated the biological activities of black pepper essential oil (BPEO) in human cells. Therefore, in the current study, we examined the biological activities of BPEO in cytokine-stimulated human dermal fibroblasts by analyzing the levels of 17 important protein biomarkers… Read more »
Black pepper (Piper nigrum) essential oil demonstrates tissue remodeling and metabolism modulating potential in human cells
Han X, Beaumont C, Rodriguez D, Bahr T Phytotherapy Research, 2018 ABSTRACT: Very few studies have investigated the biological activities of black pepper essential oil (BPEO) in human cells. Therefore, in the current study, we examined the biological activities of BPEO in cytokine-stimulated human dermal fibroblasts by analyzing the levels of 17 important protein biomarkers… Read more »
Chemistry, Antimicrobial Mechanisms, and Antibiotic Activities of Cinnamaldehyde against Pathogenic Bacteria in Animal Feeds and Human Foods
Friedman M Journal of Agricultural and Food Chemistry, 2017 ABSTRACT: Cinnamaldehyde is a major constituent of cinnamon essential oils produced by aromatic cinnamon plants. This compound has been reported to exhibit antimicrobial properties in vitro in laboratory media and in animal feeds and human foods contaminated with disease-causing bacteria including Bacillus cereus, Campylobacter jejuni, Clostridium perfringens, Escherichia… Read more »
Essential oils diversely modulate genome-wide gene expression in human dermal fibroblasts
Han X, Parker TL Cogent Medicine, 2017 ABSTRACT: The increasing popularity of essential oils for skincare has led to investigation of their biological effects in human skin cells. In this study, we investigated the biological activities of three commercially available essential oils, i.e. rosemary oil, wild orange oil, and a blend (commercial name: Deep Blue)… Read more »
Melaleuca (Melaleuca alternifolia) essential oil demonstrates tissue-remodeling and metabolism-modulating activities in human skin cells
Han X, Parker TL Cogent Biology, 2017 ABSTRACT: Melaleuca (Melaleuca alternifolia) essential oil (MEO), commonly known as tea tree oil, is popularly used in skincare products. In the current study, we investigated the biological activity of a commercially available MEO (with terpinen-4-ol as the major active component) in pre-inflamed human dermal fibroblasts, which were designed… Read more »
Anti-inflammatory activity of Juniper (Juniperus communis) berry essential oil in human dermal fibroblasts
Han X, Parker TL Cogent Medicine, 2017 ABSTRACT: Although juniper (Juniperus communis) berry essential oil (JEO) has been used in skin care products, research on its biological activity in human skin cells is scarce. In the current study, we explored the biological activity of JEO (with alpha-pinene as the major active component) in pre-inflamed human dermal… Read more »
A portion of plant airborne communication is endorsed by uptake and metabolism of volatile organic compounds
Matsui K Current opinion in plant biology, 2016 ABSTRACT: Plants have the ability to sense volatile organic compounds (VOCs) so as to efficiently adapt to their environment. The mechanisms underlying such plant ‘olfactory’ systems are largely unknown. Here I would like to propose that the metabolism of VOCs in plant tissues is one of the… Read more »
Herbal bioactivation: the good, the bad and the ugly
Zhou S, Koh HL, Gao Y, Gong ZY, Lee EJ Life sciences, 2004 ABSTRACT: It has been well established that the formation of reactive metabolites of drugs is associated with drug toxicity. Similarly, there are accumulating data suggesting the role of the formation of reactive metabolites/intermediates through bioactivation in herbal toxicity and carcinogenicity. It has… Read more »
Effects of TRP channel agonist ingestion on metabolism and autonomic nervous system in a randomized clinical trial of healthy subjects
Michlig S, Merlini JM, Beaumont M, Ledda M, Tavenard A, Mukherjee R, Camacho S, le Coutre J Scientific reports, 2016 ABSTRACT: Various lines of published evidence have already demonstrated the impact of TRPV1 agonists on energetic metabolism through the stimulation of the sympathetic nervous system (SNS). This study presents a trial investigating if stimulation of… Read more »
The pharmacokinetics of a novel anti-tumor agent, beta-elemene, in Sprague-Dawley rats
Wang K, Li Z, Chen Y, Su C
Biopharmaceutics & Drug Disposition, 2005