Plants and Surgery: The Protective Effects of Thymoquinone on Hepatic Injury-A Systematic Review of In Vivo Studies

Tekbas A, Huebner J, Settmacher U, Dahmen U International Journal of Molecular Sciences, 2018 ABSTRACT: Multimodal treatment concepts including liver transplantation for hepatocellular carcinoma (HCC), extended resection methods and neoadjuvant chemotherapy for colorectal liver metastasis significantly improve patients’ outcome. However, surgery-induced hepatic ischemia-reperfusion injury (IRI) and chemotherapy-associated hepatotoxicity result in hepatocellular damage and compromised liver… Read more »

Apoptotic Effect of Nigella sativa on Human Lymphoma U937 Cells

Arslan BA, Isik FB, Gur H, Ozen F, Catal T Pharmacognosy Magazine, 2017 OBJECTIVE: Nigella sativa is from botanical Ranunculaceae family and commonly known as black seed. Apoptotic effect of N. sativa and its apoptotic signaling pathways on U937 lymphoma cells are unknown. MATERIALS AND METHODS: In this study, we investigated selective cytotoxic and apoptotic effects of N. sativa extract… Read more »