A Comparative Evaluation of the Cytotoxic and Antioxidant Activity of Mentha crispa Essential Oil, Its Major Constituent Rotundifolone, and Analogues on Human Glioblastoma

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Turkez H, Tozlu OO, Lima TC, De brito AEM, De sousa DP Oxidative Medicine and Cellular Longevity, 2018 ABSTRACT: Cancer is a major public health problem around the globe. This disorder is affected by alterations in multiple physiological processes, and oxidative stress has been etiologically implicated in its pathogenesis. Glioblastoma (GBM) is considered the most… Read more »

Structural relationships and vasorelaxant activity of monoterpenes

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Lima TC, Mota MM, Barbosa-Filho JM, Viana Dos Santos MR, De Sousa DP Daru, 2012 ABSTRACT: Background and purpose of the study The hypotensive activity of the essential oil of Mentha x villosa and its main constituent, the monoterpene rotundifolone, have been reported. Therefore, our objective was to evaluate the vasorelaxant effect of monoterpenes found… Read more »