Safranal protects against beta-amyloid peptide-induced cell toxicity in PC12 cells via MAPK and PI3 K pathways

Rafieipour F, Hadipour E, Emami SA, Asili J, Tayarani-najaran Z Metabolic Brain Disease, 2018 ABSTRACT: Alzheimer’s disease is a type of cerebrovascular problem with progressive mental disabilities for the patient. This study aimed to investigate the protective effect of safranal on toxicity and oxidative damage induced by beta-amyloid (Aβ) and hydrogen peroxide (H2O2) in PC12… Read more »

Protective effects of saffron and its active components against oxidative stress and apoptosis in endothelial cells

Rahiman N, Akaberi M, Sahebkar A, Emami SA, Tayarani-Najaran Z Microvascular Research, 2018 ABSTRACT: In this study, we investigated the role of mitogen-activated protein kinase (MAPK) signaling pathways in mediation of the protective effects of saffron extract, saffron essential oil, safranal and crocin on bovine aortic endothelial cells against oxidative injury. The viability of cells… Read more »