Copaiba oil effect under different pathways in mice subjected to sepsis

Botelho NM, Silveira EL, Lopes LN, Santos FA, Teixeira RK, Silva TT Acta Cirurgica Brasileira, 2017 PURPOSE: To evaluate the effects of copaiba oil administered by different routes on survival of mices subjected to cecal ligation and puncture. METHODS: Thirty two mice were distributed into four study groups (N=8): Sham group: normal standard animals; CONTROL GROUP: submitted… Read more »

Effects of Carvacrol on Survival, Mesenteric Blood Flow, Aortic Function and Multiple Organ Injury in a Murine Model of Polymicrobial Sepsis

Ozer EK, Goktas MT, Toker A, Bariskaner H, Ugurluoglu C, Iskit AB Inflammation, 2017 ABSTRACT: Carvacrol (CRV) has strong cytoprotective, antioxidant, and anti-inflammatory properties. We aimed to demonstrate the possible protective effects of CRV on survival, mesenteric artery blood flow (MBF), vascular reactivity, and oxidative and inflammatory injuries in a murine model of polymicrobial sepsis induced by cecal ligation and puncture… Read more »