Selected terpenes from leaves of Ocimum basilicum L. induce hemoglobin accumulation in human K562 cells

Giordana F, Nicola M, Valentina C, Torricelli P, Beninati S, Tagliati F, Mischiati C Fitoterapia, 2018 ABSTRACT: Re-expression of fetal hemoglobin (HbF) was proposed as a possible therapeutic strategy for β-haemoglobinopathies. Although several inducers of HbF were tested in clinical trials, only hydroxyurea (HU) received FDA approval. Despite it produced adequate HbF levels only in… Read more »

Can Ocimum basilicum relieve chronic unpredictable mild stress-induced depression in mice?

Ayuob NN, Firgany AEL, El-Mansy AA, Ali S Experimental and Molecular Pathology BACKGROUND: Depression is one of the important world-wide health problems. OBJECTIVES: This study aimed to assess the ameliorative effect of Ocimum basilicum (OB) essential oil on the behavioral, biochemical and histopathological changes resulted from exposure to chronic unpredictable mild stress (CUMS). It also aimed to… Read more »

Evaluation of the chemical composition, antioxidant and anti-inflammatory activities of distillate and residue fractions of sweet basil essential oil

Li H, Ge Y, Luo Z, Zhou Y, Zhang X, Zhang J, Fu Q Journal of Food Science and Technology, 2017 ABSTRACT: In this study, the chemical composition and antioxidant and anti-inflammatory activities of sweet basil (Ocimum basilicum L. Lamiaceae family) were evaluated. Sweet basil is a food-related plant that is widely used in traditional Chinese medicine. Sweet basil crude oil was… Read more »