Essential Oil as a Potential Anti-Acne Topical Nanoemulsion-In Vitro and In Vivo Study

Taleb MH, Abdeltawab NF, Shamma RN, Abdelgayed SS, Mohamed SS, Farag MA, Ramadan MA Molecules, 2018 ABSTRACT: Antibiotics are often prescribed in acne treatment; however, Propionibacterium acnes and Staphylococcus epidermidis, the two of the major acne-associated bacteria, developed antibiotic resistance. Essential oils (EOs) present a natural, safe, efficacious and multifunctional alternative treatment. This study aimed… Read more »

Antidepressant-Like Effect of Lippia sidoides (Verbenaceae) Essential Oil and Its Major Compound Thymol in Mice

Parente MSR, Custódio FR, Cardoso NA, Lima MJA, Melo TS, Linhares MI, Siqueira RMP, Nascimento AÁD, Catunda Júnior FEA, Melo CTV Scientia Pharmaceutica, 2018 ABSTRACT: Depression is a common disease affecting more than 300 million people worldwide. Since Lippia sidoides has shown central nervous system effects in previous works, we aimed to investigate the effect… Read more »

Thymol, thyme, and other plant sources: Health and potential uses

Salehi B, Mishra AP, Shukla I, Sharifi-Rad M, Contreras MDM, Segura-Carretero A, Fathi H, Nasrabadi NN, Kobarfard F, Sharifi-Rad J Phytotherapy Research, 2018 ABSTRACT: Thymol is a naturally occurring phenol monoterpene derivative of cymene and isomer of carvacrol. Thymol (10-64%) is one of the major constituent of essential oils of thyme (Thymus vulgaris L., Lamiaceae),… Read more »

Citrus fruit extracts with carvacrol and thymol eliminated 7-log acid-adapted Escherichia coli O157:H7, Salmonella typhimurium, and Listeria monocytogenes: A potential of effective natural antibacterial agents

Chung D, Cho TJ, Rhee MS Food Research International, 2018 ABSTRACT: Despite the widespread belief that citrus fruit extracts (CFEs) are microbiologically safe due to their acidity, limited bactericidal effect results in low applicability as antibacterial agent and outbreaks occurred by acid-adapted pathogens. Here, we examined the antibacterial effects of CFEs [lime (Citrus medica), lemon… Read more »

Use of micronucleus and comet assay to evaluate evaluate the genotoxicity of oregano essential oil (Origanum vulgare l. Virens) in rats orally exposed for 90 days

Llana-Ruiz-Cabello M, Puerto M, Maisanaba S, Guzmán-Guillén R, Pichardo S, Cameán AM Journal of Toxicology and Environmental Health Part A, 2018 ABSTRACT: Essential oils from Origanum spp. exhibit antioxidant and antimicrobial activities making them suitable for use as food additives. The incorporation of oregano essential oil in active food packaging is under study; however, it… Read more »

Proteinaceous microspheres as a delivery system for carvacrol and thymol in antibacterial applications

Sokolik CG, Ben-Shabat-Binyamini R, Gedanken A, Lellouche JP Ultrasonics & Sonochemistry, 2017 ABSTRACT: There is an urgent need for new materials with antimicrobial activity. Phenolic essential oil (EO) compounds with Generally Recognized As Safe (GRAS) status are attractive candidates, but they need suitable delivery systems to overcome specific drawbacks. Core-shell microspheres (MSs) of Bovine Serum Albumin (BSA)… Read more »

Acaricidal Activity and Synergistic Effect of Thyme Oil Constituents against Carmine Spider Mite (Tetranychus Cinnabarinus (Boisduval))

Wu L, Huo X, Zhou X, Zhao D, He W, Liu S, Liu H, Feng T, Wang C Molecules, 2017 ABSTRACT: Studies examining the use of essential oils as replacements for synthetic insecticides require an understanding of the contribution of each constituent present, interactions among these components, and how they relate to overall toxicity. In the present… Read more »

The clinical evaluation of Vi-one chlorhexidine mouthwash on plaque-induced gingivitis: A double-blind randomized clinical trial

Amoian B, Omidbakhsh M, Khafri S Electronic Physician, 2017 BACKGROUND: Chlorhexidine (CHX) is the most effective antiseptic mouthwash to date. Essential oil such as thymol, have inhibitory and biocidal effects a range of bacteria. OBJECTIVE: To determine the effect of mouthwash containing CHX and thymol on plaque induced gingivitis. METHODS: This double-blind randomized clinical trial study was… Read more »

Perspectives on medicinal properties of natural phenolic monoterpenoids and their hybrids

Rajput JD, Bagul SD, Pete UD, Zade CM, Padhye SB, Bendre RS Molecular Diversity, 2017 ABSTRACT: Carvacrol, thymol and eugenol belong to a class of naturally presenting phenols with a ten-carbon unit, which are present in essential oils of many plants. These versatile molecules are incorporated as useful ingredients in many food products and find applications in… Read more »

Carvacrol-rich oregano oil and thymol-rich thyme red oil inhibit biofilm formation and the virulence of uropathogenic Escherichia coli

Lee JH, Kim YG, Lee J Journal of Applied Microbiology, 2017 AIMS: Urinary tract infections are caused primarily by uropathogenic Escherichia coli (UPEC), and indwelling catheters are usually colonized by UPEC biofilms tolerant to common antibiotics. Hence, UPEC biofilms pose a substantial challenge, and there is an urgent need for effective control strategies. METHODS AND… Read more »