Amiresmaeili A, Roohollahi S, Mostafavi A, Askari N Research in Pharmaceutical Sciences, 2018 ABSTRACT: The aim of the present study was to evaluate the effects of oregano essential oil (OEO) on the hippocampus and prefrontal cortex TLR 2/4 gene expression and depressive like behavior induced by chronic unpredictable stress (CUS). Sucrose preference and forced swim… Read more »
Trans-caryophyllene inhibits amyloid β (Aβ) oligomer-induced neuroinflammation in BV-2 microglial cells
Hu Y, Zeng Z, Wang B, Guo S International Immunopharmacology, 2017 ABSTRACT: Amyloid β (Aβ) is the major component of senile plaques (SP) in the brains of Alzheimer’s disease (AD) patients, and serves as an inflammatory stimulus for microglia. Trans-caryophyllene (TC), a major component in the essential oils derived from various species of medicinal plants, has displayed… Read more »