Matsubara E, Shimizu K, Fukagawa M, Ishizi Y, Kakoi C, Hatayama T, Nagano J, Okamoto T, Ohnuki K, Kondo R
Biomedical Research, 2012
The perennial grass Vetiveria zizanioides (vetiver) is mainly cultivated for its fragrant essential oil. Although the components of the oil and their biological activities have been studied extensively, the effect of the volatiles emitted from the roots of V. zizanioides on humans has so far remained unexplored. We investigated the effects of volatile compounds emitted from the cut roots of V. zizanioides (1.0 g, low-dose conditions; 30 g, high-dose conditions) on individuals during a visual display terminal task. Participants who breathed the volatile compounds emitted under low-dose conditions showed faster reaction times and stimulation of sympathetic nerve activity as measured by electrocardiography. These effects were not observed under high-dose conditions. The total amount of volatiles emitted during the experiment was 0.25 μg under low-dose conditions and 1.35 μg under high-dose conditions. These findings indicate that volatile compounds emitted from the roots of V. zizanioides under low-dose conditions may have helped subjects to maintain performance in visual discrimination tasks while maintaining high sympathetic nerve system activity.
Matsubara E, Shimizu K, Fukagawa M, Et Al. Volatiles emitted from the roots of Vetiveria zizanioides suppress the decline in attention during a visual display terminal task. Biomed Res. 2012;33(5):299-308.