Analgesic-Like Activity of Essential Oil Constituents: An Update

de Cássia da Silveira E, Sá R, Lima TC, da Nóbrega FR, de Brito AEM, de Sousa DP International Journal of Molecular Science, 2017 ABSTRACT: The constituents of essential oils are widely found in foods and aromatic plants giving characteristic odor and flavor. However, pharmacological studies evidence its therapeutic potential for the treatment of several… Read more »

Effects of topical and systemic administration of Eugenia caryophyllata buds essential oil on corneal anesthesia and analgesia

Khalilzadeh E, Hazrati R, Saiah GV Research in pharmaceutical sciences, 2016 ABSTRACT: Clinical studies suggest that essential oil of Eugenia caryophyllata (Clove) buds (EOEC) is efficacious in the treatment of dental pain. In the present study, we investigated the analgesic and local anesthetic effects of EOEC and its possible mechanisms of action in acute corneal… Read more »

Effects of monoterpenes on ion channels of excitable cells

Oz M, Lozon Y, Sultan A, Yang KH, Galadari S Pharmacology & therapeutics, 2015 ABSTRACT: Monoterpenes are a structurally diverse group of phytochemicals and a major constituent of plant-derived ‘essential oils’. Monoterpenes such as menthol, carvacrol, and eugenol have been utilized for therapeutical purposes and food additives for centuries and have been reported to have… Read more »

The bioactivity and toxicological actions of carvacrol

Suntres ZE, Coccimiglio J, Alipour M Critical Reviews in Food Science and Nutrition, 2015 ABSTRACT: Carvacrol is a monoterpenic phenol produced by an abundant number of aromatic plants, including thyme and oregano. Presently, carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations…. Read more »