The Effects of Various Essential Oils on Epilepsy and Acute Seizure: A Systematic Review

Bahr TA, Rodriguez D, Beaumont C, Allred K Evidence Based Complementary and Alternative Medicine, 2019 ABSTRACT: Many essential oils (EOs) have anticonvulsant activity and might benefit people with epilepsy. Lemongrass, lavender, clove, dill, and other EOs containing constituents such as asarone, carvone, citral, eugenol, or linalool are good candidates for evaluation as antiepileptic drugs. On… Read more »

(+)-Dehydrofukinone modulates membrane potential and delays seizure onset by GABAa receptor-mediated mechanism in mice

Garlet QI, da Costa Pires L, Milanesi LH, Marafiga JR, Baldisserotto B, de Mello CF, Heinzmann BM Toxicology and Applied Pharmacology, 2017 ABSTRACT: (+)-Dehydrofukinone (DHF), isolated from Nectandra grandiflora (Lauraceae) essential oil, induces sedation and anesthesia by modulation of GABAa receptors. However, no study has addressed whether DHF modulates other cellular events involved in the control of cellular excitability, such as seizure… Read more »

Neuron differentiation-related genes are up-regulated in the hypothalamus of odorant-inhaling rats subjected to acute restraint stress.

Nakamura A, Fujiwara S, Ishijima T, Okada S, Nakai Y, Matsumoto I, Misaka T, Abe K Journal of agricultural and food chemistry, 2010 ABSTRACT: To elucidate some physiopsychological effects of a pleasant odor, we analyzed gene expression profiles in the hypothalamus of rats which, under a restraint-stressed condition, inhaled (R)-(-)-linalool. Consequently, 697 probe sets showed… Read more »