Evaluation of Skin Irritation and Acute and Subacute Oral Toxicity of Essential Oils in Rabbit and Mice

Mekonnen A, Tesfaye S, Christos SG, Dires K, Zenebe T, Zegeye N, Shiferaw Y, Lulekal E Journal of Toxicology, 2019 ABSTRACT: Lavandula angustifolia is used in traditional and folk medicines of Ankober District, North Central Ethiopia, for the treatment of several livestock and human disorders. This toxicity study aimed to investigate L. angustifolia essential oil… Read more »

Lavandula angustifolia Essential Oil and Linalool Counteract Social Aversion Induced by Social Defeat

Caputo L, Reguilon MD, Mińarro J, De feo V, Rodriguez-arias M Molecules, 2018 ABSTRACT: Many vegetable extracts, essential oils, and their main constituents are active on the Central Nervous System (CNS). In fact, they have been used as sedatives, hypnotics, or tranquilizers for their activity in treating CNS disorders. In this research, we studied the… Read more »

Essential oil obtained from micropropagated lavender, its effect on HSF cells and application in cosmetic emulsion as a natural protective substance

Andrys D, Adaszyńska-Skwirzyńska M, Kulpa D Natural Product Research, 2017 ABSTRACT: The aim of the study was to determine the influence of the essential oils isolated from the field – grown and micropropagated in vitro narrow – leaved lavender of the ‘Munstead’ cultivar, on human skin cells, and their capability to synthesise procollagen. The amount… Read more »

Exploring Pharmacological Mechanisms of Lavender (Lavandula angustifolia) Essential Oil on Central Nervous System Targets

López V, Nielsen B, Solas M, Ramírez MJ, Jäger AK Frontiers in Pharmacology, 2017 ABSTRACT: Lavender essential oil is traditionally used and approved by the European Medicines Agency (EMA) as herbal medicine to relieve stress and anxiety. Some animal and clinical studies reveal positive results in models of anxiety and depression although very little research has… Read more »

Unraveling the rat blood genome-wide transcriptome after oral administration of lavender oil by a two-color dye-swap DNA microarray approach

Hori M, Kubo H, Shibato J, Saito T, Ogawa T, Wakamori M, Masuo Y, Shioda S, Rakwal R Genomics data, 2016 ABSTRACT: Lavender oil (LO) is a commonly used essential oil in aromatherapy as non-traditional medicine. With an aim to demonstrate LO effects on the body, we have recently established an animal model investigating the… Read more »

Subconscious olfactory influences of stimulant and relaxant odors on immune function

Trellakis S, Fischer C, Rydleuskaya A, Tagay S, Bruderek K, Greve J, Lang S, Brandau S
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology – Head and Neck Surgery, 2012

Linalool and beta-pinene exert their antidepressant-like activity through the monoaminergic pathway

Guzmán-Gutiérrez SL, Bonilla-Jaime H, Gómez-Cansino R, Reyes-Chilpa R. Life Sciences, 2015 ABSTRACT: AIMS: Linalool and β-pinene are two volatile monoterpenes that possess antidepressant-like activity. These are components of many aromatic plants used in folk medicine around the world to relieve anxiety and depression. In this contribution, we focused on examining the mechanism of action of… Read more »