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Effects of oregano essential oil on brain TLR4 and TLR2 gene expression and depressive-like behavior in a rat model

Posted April 3, 2018 by by Kathryn Allred

Amiresmaeili A, Roohollahi S, Mostafavi A, Askari N Research in Pharmaceutical Sciences, 2018 ABSTRACT: The aim of the present study was to evaluate the effects of oregano essential oil (OEO) on the hippocampus and prefrontal cortex TLR 2/4 gene expression and depressive like behavior induced by chronic unpredictable stress (CUS). Sucrose preference and forced swim… Read more »

Trans-caryophyllene inhibits amyloid β (Aβ) oligomer-induced neuroinflammation in BV-2 microglial cells

Posted August 31, 2017 by by Tyler Bahr

Hu Y, Zeng Z, Wang B, Guo S International Immunopharmacology, 2017 ABSTRACT: Amyloid β (Aβ) is the major component of senile plaques (SP) in the brains of Alzheimer’s disease (AD) patients, and serves as an inflammatory stimulus for microglia. Trans-caryophyllene (TC), a major component in the essential oils derived from various species of medicinal plants, has displayed… Read more »

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