The Effect of Thymoquinone on Apoptosis of SK-OV-3 Ovarian Cancer Cell by Regulation of Bcl-2 and Bax

Liu X, Dong J, Cai W, Pan Y, Li R, Li B International Journal of Gynecological Cancer, 2017 ABSTRACT: OBJECTIVE: We aim to determine how cisplatin, thymoquinone (TQ), and combination regimen can affect apoptosis of cultured SK-OV-3 cells. We also want to explore the mechanism of these influences on the cells’ apoptosis by Bcl-2 and Bax gene. METHOD/MATERIALS: Cell Counting Kit-8 assay… Read more »

Antitumor phenylpropanoids found in essential oils

Carvalho AA, Andrade LN, de Sousa ÉB, de Sousa DP Biomed Research International, 2015  ABSTRACT: The search for new bioactive substances with anticancer activity and the understanding of their mechanisms of action are high-priorities in the research effort toward more effective treatments for cancer. The phenylpropanoids are natural products found in many aromatic and medicinal… Read more »