Antimicrobial Survey of Local Herbal Drugs against Isolated from Patients Admitted to a Level-I Trauma Center

de Macêdo DG, Souza MMA, Morais-Braga MFB, Coutinho HDM, Dos Santos ATL, da Cruz RP, da Costa JGM, Rodrigues FFG, Quintans-Junior LJ, da Silva Almeida JRG, de Menezes IRA
Bulletin of Emergency and Trauma,


OBJECTIVE: To determine the antimicrobial activity and entity of several local herbal plants against Acintobacters isolated from trauma patients admitted to a Level-I trauma center.

METHODS: The antibacterial activities of the Satureja bachtiarica oil and someselected Iranian medicinal plants (Artemisia sieberi and Tanacetum dumosum belonging to the Asteraceae/Compositae; Salvia mirzayanii and Mentha mozaffarianii belonging to the Lamiaceae/Labiatae) were assayed on A. baumannii by microdilution and agar disc diffusion methods. Having obtained the acceptable antibacterial data, the shade-dried aerial parts of the plants were extracted by hydrodistillation method using Clevenger apparatus according to European pharmacopeia for 3 h. The analysis of S. bachtiarica essential oil accompanied by other herbal drug oils were performed by using GC/FID and GC/MS methods.

RESULTS: Outcomes revealed that the S. bachtiarica essential oil exhibited the potent antibacterial capability against Acinetobacter strains in comparison with Colistin, as a positive control. For S. bachtiarica,the growth inhibition zone and minimum inhibitory concentration (MIC) values were 21 mm and 0.5 mg/ml, while, for Colistin, the data were in order: 8 mm and 0.016 mg/ml. Consequently, GC/MS outcomes demonstrated that the major components of the essence were carvacrol (48.6%), followed by p-Cymene (16.6%), γ-terpinene (6.9%) and linalool (5.3%).

CONCLUSION: Based on the considerable inhibitory activity against nosocomial infections by essential oil of S. bachtiarica, it could be considered as the suitable candidate in the food industry and pharmaceutical uses.


Abdolrahimzadeh H, Bolandparvaz S, Abbasi HR, et al. Antimicrobial Survey of Local Herbal Drugs against Isolated from Patients Admitted to a Level-I Trauma Center. Bull Emerg Trauma. 2018;6(4):355-362.

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