Antimicrobial Survey of Local Herbal Drugs against Isolated from Patients Admitted to a Level-I Trauma Center

de Macêdo DG, Souza MMA, Morais-Braga MFB, Coutinho HDM, Dos Santos ATL, da Cruz RP, da Costa JGM, Rodrigues FFG, Quintans-Junior LJ, da Silva Almeida JRG, de Menezes IRA Bulletin of Emergency and Trauma, 2018 ABSTRACT: OBJECTIVE: To determine the antimicrobial activity and entity of several local herbal plants against Acintobacters isolated from trauma patients admitted to… Read more »

Citrus fruit extracts with carvacrol and thymol eliminated 7-log acid-adapted Escherichia coli O157:H7, Salmonella typhimurium, and Listeria monocytogenes: A potential of effective natural antibacterial agents

Chung D, Cho TJ, Rhee MS Food Research International, 2018 ABSTRACT: Despite the widespread belief that citrus fruit extracts (CFEs) are microbiologically safe due to their acidity, limited bactericidal effect results in low applicability as antibacterial agent and outbreaks occurred by acid-adapted pathogens. Here, we examined the antibacterial effects of CFEs [lime (Citrus medica), lemon… Read more »

Use of micronucleus and comet assay to evaluate evaluate the genotoxicity of oregano essential oil (Origanum vulgare l. Virens) in rats orally exposed for 90 days

Llana-Ruiz-Cabello M, Puerto M, Maisanaba S, Guzmán-Guillén R, Pichardo S, Cameán AM Journal of Toxicology and Environmental Health Part A, 2018 ABSTRACT: Essential oils from Origanum spp. exhibit antioxidant and antimicrobial activities making them suitable for use as food additives. The incorporation of oregano essential oil in active food packaging is under study; however, it… Read more »

Efficacy of poly(lactic acid)/carvacrol electrospun membranes against Staphylococcus aureus and Candida albicans in single and mixed cultures

Scaffaro R, Lopresti F, D’Arrigo M, Marino A, Nostro A Applied Microbiology and Biotechnology, 2018 ABSTRACT: Carvacrol (CAR) is one of the most promising essential oil components with antimicrobial activity. New technologies aimed to incorporate this active molecule into carrier matrix to improve the stability and prolong the biological activity. The goal of this study… Read more »

Anti-inflammatory, tissue remodeling, immunomodulatory, and anticancer activities of oregano (Origanum vulgare) essential oil in a human skin disease model

Han X, Parker TL Biochimie Open, 2017 ABSTRACT: The use of oregano (Origanum vulgare) essential oil (OEO) has become popular in skin care products. However, scientific research regarding its effects on human skin cells is scarce. In this study, we investigated the biological activity of a commercially available OEO, which is high in carvacrol content,… Read more »

Alcoholic monoterpenes found in essential oil of aromatic spices reduce allergic inflammation by the modulation of inflammatory cytokines

Pina LTS, Ferro JNS, Rabelo TK, Oliveira MA, Scotti L, Scotti MT, Walker CIB, Barreto EO, Quintans Júnior LJ, Guimarães AG Natural Product Research, 2018 ABSTRACT: Allergic inflammation is a response of the body against pathogens by cytokine release and leucocyte recruitment. Recently, there was an increase in morbimortality associated with allergic inflammation, especially asthma…. Read more »

Effect of oregano essential oil and carvacrol on Cryptosporidium parvum infectivity in HCT-8 cells

Gaur S, Kuhlenschmidt TB, Kuhlenschmidt MS, Andrade JE Parasitology International, 2017 ABSTRACT: Cryptosporidium parvum is the second leading cause of persistent diarrhea among children in low-resource settings. This study examined the effect of oregano essential oil (OEO) and carvacrol (CV) on inhibition of C. parvum infectivity in vitro. HCT-8 cells were seeded (1×106) in 96-well microtiter plates… Read more »

Proteinaceous microspheres as a delivery system for carvacrol and thymol in antibacterial applications

Sokolik CG, Ben-Shabat-Binyamini R, Gedanken A, Lellouche JP Ultrasonics & Sonochemistry, 2017 ABSTRACT: There is an urgent need for new materials with antimicrobial activity. Phenolic essential oil (EO) compounds with Generally Recognized As Safe (GRAS) status are attractive candidates, but they need suitable delivery systems to overcome specific drawbacks. Core-shell microspheres (MSs) of Bovine Serum Albumin (BSA)… Read more »

Selective Essential Oils from Spice or Culinary Herbs Have High Activity against Stationary Phase and Biofilm Borrelia burgdorferi

Feng J, Zhang S, Shi W, Zubcevik N, Miklossy J, Zhang Y Frontiers in Medicine, 2017 ABSTRACT: Although the majority of patients with acute Lyme disease can be cured with the standard 2-4 week antibiotic treatment, about 10-20% of patients continue suffering from chronic symptoms described as posttreatment Lyme disease syndrome. While the cause for this… Read more »

Carvacrol and eugenol effectively inhibit Rhizopus stolonifer and control postharvest soft rot decay in peaches

Zhou D, Wang Z, Li M, Xing M, Xian T, Tu K Journal of Applied Microbiology AIMS: This study aimed to investigate the antifungal mechanism of carvacrol and eugenol to inhibit Rhizopus stolonifer and the control of postharvest soft rot decay in peaches. METHODS AND RESULTS: For antifungal mechanism, effects of carvacrol and eugenol on… Read more »