Repeated-doses and reproductive toxicity studies of the monoterpene 1,8-cineole (eucalyptol) in Wistar rats

Caldas GF, Limeira MM, Araújo AV, Albuquerque GS, Silva-Neto JD, Silva TG, Costa-Silva JH, Menezes IR, Costa JG, Wanderley AG Food and Chemical Toxicology, 2016 ABSTRACT: 1,8-cineole (eucalyptol) is widely used as an excipient in the pharmaceutical industry and as a food flavoring agent, thus providing significant potential for human exposure to the compound. We… Read more »

Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral

Adukwu EC, Bowles M, Edwards-Jones V, Bone H Applied microbiology and biotechnology, 2016 ABSTRACT: The aim of this study was to determine the antimicrobial effects of lemongrass essential oil (C. flexuosus) and to determine cytotoxic effects of both test compounds on human dermal fibroblasts. Antimicrobial susceptibility screening was carried out using the disk diffusion method…. Read more »

Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 Cells In Vitro and In Vivo

Lu X, Yang L, Lu C, Xu Z, Qiu H, Wu J, Wang J, Tong J, Zhu Y, Shen J BioMed Research International, 2016 ABSTRACT: Nowadays, chemotherapy is still the main effective treatment for cancer. Herb prescriptions containing Pogostemon cablin Benth (also known as “Guang-Huo-Xiang”) have been widely used in Chinese medicine today. In our… Read more »

Plant Secondary Metabolites as Rodent Repellents: a Systematic Review

Hansen SC, Stolter C, Imholt C, Jacob J J Chem Ecol, 2016 ABSTRACT: The vast number of plant secondary metabolites (PSMs) produced by higher plants has generated many efforts to exploit their potential for pest control. We performed a systematic literature search to retrieve relevant publications, and we evaluated these according to PSM groups to… Read more »

Sedative effect of central administration of Coriandrum sativum essential oil and its major component linalool in neonatal chicks

Gastón MS, Cid MP, Vázquez AM, Decarlini MF, Demmel GI, Rossi LI, Aimar ML, Salvatierra NA Pharmaceutical Biology, 2016 ABSTRACT: Context Coriandrum sativum L. (Apiaceae) (coriander) is an herb grown throughout the world as a culinary, medicinal or essential crop. In traditional medicine, it is used for the relief of anxiety and insomnia. Systemic hydro-alcoholic… Read more »

Identification of miRNAs and their targets involved in the secondary metabolic pathways of Mentha spp

Singh N, Srivastava S, Shasany AK, Sharma A Computational Biology and Chemistry, 2016 ABSTRACT: The endogenous, small and non-coding functional microRNAs govern the regulatory system of gene expression and control the growth and development of the plants. Mentha spp. are well known herbs for its flavor, fragrance and medicinal properties. In the present study, we… Read more »

1, 8-Cineol Protect Against Influenza-Virus-Induced Pneumonia in Mice

Li Y, Lai Y, Wang Y, Liu N, Zhang F, Xu P Inflammation, 2016 ABSTRACT: 1,8-Cineol is a major monoterpene principally from eucalyptus essential oils and has been shown to exert anti-inflammatory, antiviral, and inhibitory of nuclear factor (NF)-kB effect. In the present study, we evaluated the effect of 1,8-cineol on mice infected with influenza… Read more »

Effects of topical and systemic administration of Eugenia caryophyllata buds essential oil on corneal anesthesia and analgesia

Khalilzadeh E, Hazrati R, Saiah GV Research in pharmaceutical sciences, 2016 ABSTRACT: Clinical studies suggest that essential oil of Eugenia caryophyllata (Clove) buds (EOEC) is efficacious in the treatment of dental pain. In the present study, we investigated the analgesic and local anesthetic effects of EOEC and its possible mechanisms of action in acute corneal… Read more »

Geraniol improves the impaired vascular reactivity in diabetes and metabolic syndrome through calcium channel blocking effect

El-Bassossy HM, Elberry AA, Ghareib SA Journal of Diabetes and Its Complications, 2016 ABSTRACT: AIM: The aim of the present study is to investigate the effect and possible mechanism of action of geraniol on the impaired vascular reactivity of aortic rings isolated from diabetes or metabolic syndrome (MS) -induced rats. METHODS: Male Wistar rats were… Read more »

The influence of environmentally friendly pesticide – Eucalyptol – alone and in combination with terpinen-4-ol – on model bacterial membranes

Hąc-Wydro K, Szydło K Colloids and surfaces. B, Biointerfaces, 2016 ABSTRACT: Eucalyptus oil is known from antimicrobial properties and due to natural origin and low toxicity it can be applied as a green pesticide. This plant extract is a mixture of compounds among which Eucalyptol prevails strongly over the number of minor components including terpinen-4-ol…. Read more »