Srivilai J, Waranuch N, Tangsumranjit A, Khorana N, Ingkaninan K Drug Delivery & Translational Research, 2017 ABSTRACT: Minoxidil is approved for topical treatment of androgenic alopecia but hampered by poor cutaneous absorption. Recently, the randomized control trial showed that hair loss treatment of minoxidil was improved by co-application of the anti-androgen, Curcuma aeruginosa Roxb. extract…. Read more »
Antifungal activity of Myrtus communis against Malassezia sp. isolated from the skin of patients with pityriasis versicolor
Barac A, Donadu M, Usai D, Spiric VT, Mazzarello V, Zanetti S, Nikolic E, Stevanovic G, Popovic N, Rubino S Infection, 2017 ABSTRACT: The increasing incidence of fungal infections and antifungal resistance has prompted the search for novel antifungal drugs and alternative agents. We explored the antifungal activity of Myrtus communis essential oil (EO) against Malassezia sp…. Read more »
The Use of Aromatherapy for Postoperative Pain Management: A Systematic Review of Randomized Controlled Trials
Dimitriou V, Mavridou P, Manataki A, Damigos D Journal of Perianesthesia Nursing, 2017 PURPOSE: Aromatherapy (AT) is a complementary therapy recently used in the perianesthetic period. However, the scientific data on its effectiveness are limited. The aim of this systematic review is to present and analyze the results of all randomized controlled trials (RCTs) that studied… Read more »
Chemistry, Antimicrobial Mechanisms, and Antibiotic Activities of Cinnamaldehyde against Pathogenic Bacteria in Animal Feeds and Human Foods
Friedman M Journal of Agricultural and Food Chemistry, 2017 ABSTRACT: Cinnamaldehyde is a major constituent of cinnamon essential oils produced by aromatic cinnamon plants. This compound has been reported to exhibit antimicrobial properties in vitro in laboratory media and in animal feeds and human foods contaminated with disease-causing bacteria including Bacillus cereus, Campylobacter jejuni, Clostridium perfringens, Escherichia… Read more »
Effect of oregano essential oil and carvacrol on Cryptosporidium parvum infectivity in HCT-8 cells
Gaur S, Kuhlenschmidt TB, Kuhlenschmidt MS, Andrade JE Parasitology International, 2017 ABSTRACT: Cryptosporidium parvum is the second leading cause of persistent diarrhea among children in low-resource settings. This study examined the effect of oregano essential oil (OEO) and carvacrol (CV) on inhibition of C. parvum infectivity in vitro. HCT-8 cells were seeded (1×106) in 96-well microtiter plates… Read more »
Anti-amyloidogenic and anti-apoptotic effect of α-bisabolol against Aβ induced neurotoxicity in PC12 cells
Shanmuganathan B, Suryanarayanan V, Sathya S, Narenkumar M, Singh SK, Ruckmani K, Pandima Devi K European Journal of Medicinal Chemistry, 2017 ABSTRACT: Alzheimer’s disease (AD) is a life-threatening neurodegenerative disorder leading to dementia, with a progressive decline in memory and other thinking skills of elderly populace. Of the multiple etiological factors of AD, the accumulation… Read more »
In vitro Protoscolicidal Effects of Cinnamomum zeylanicum Essential Oil and Its Toxicity in Mice
Mahmoudvand H, Mahmoudvand H, Oliaee RT, Kareshk AT, Mirbadie SR, Aflatoonian MR Pharmacognosy Magazine, 2017 BACKGROUND: This study investigates the scolicidal effects of Cinnamomum zeylanicum essential oilagainst the protoscoleces of hydatid cysts and its toxicity in the mice model. MATERIALS AND METHODS: Gas chromatography/mass spectroscopy analyses were used to identify the constituents of essential oil. Protoscoleces were treated… Read more »
Apoptotic Effect of Nigella sativa on Human Lymphoma U937 Cells
Arslan BA, Isik FB, Gur H, Ozen F, Catal T Pharmacognosy Magazine, 2017 OBJECTIVE: Nigella sativa is from botanical Ranunculaceae family and commonly known as black seed. Apoptotic effect of N. sativa and its apoptotic signaling pathways on U937 lymphoma cells are unknown. MATERIALS AND METHODS: In this study, we investigated selective cytotoxic and apoptotic effects of N. sativa extract… Read more »
Construction of cell factories for high production of nerolidol in Saccharomyces cerevisiae (Chinese)
Zhang LL, Ma XL, Wang D, Yu P, Huang LQ, Zhang XL, Dai ZB Zhongguo Zhong Yao Za Zhi, 2017 ABSTRACT: Nerolidol is an important constituent of terpenoid essential oil and has excellent anti-tumor, anti-bacterial, and anti-oxidative properties. For realizing heterogenous production of nerolidol, our research firstly integrated the codon-optimized Actinidia sinensis nerolidol synthase gene (NES) into the… Read more »
Proteinaceous microspheres as a delivery system for carvacrol and thymol in antibacterial applications
Sokolik CG, Ben-Shabat-Binyamini R, Gedanken A, Lellouche JP Ultrasonics & Sonochemistry, 2017 ABSTRACT: There is an urgent need for new materials with antimicrobial activity. Phenolic essential oil (EO) compounds with Generally Recognized As Safe (GRAS) status are attractive candidates, but they need suitable delivery systems to overcome specific drawbacks. Core-shell microspheres (MSs) of Bovine Serum Albumin (BSA)… Read more »