Anethole

  • Backbone: Monoterpene
  • Functional Group: Phenylpropene

Fennel main constituent, trans‑anethole treatment against LPS‑induced acute lung injury by regulation of Th17/Treg function

Zhang S, Chen X, Devshilt I, Yun Q, Huang C, An L, Dorjbat S, He X Molecular Medicine Reports, 2018 ABSTRACT: Fennel, commonly used in traditional Chinese medicine, is known as Foeniculum vulgare Mill. And its clinical application has been shown to target many biological systems including gastroenterology, endocrinology, gynecology and respiratory. The main constituent… Read more »

Terpenes, Phenylpropanoids, Sulfur and Other Essential Oil Constituents as Inhibitors of Cholinesterases

Politeo O, Burcul F, Blazevic I, Radan M Current Medicinal Chemistry, 2018 ABSTRACT: Essential oils constituents are a diverse family of low molecular weight organic compounds with comprehensive biological activity. According to their chemical structure these active compounds can be divided into four major groups: terpenes, terpenoids, phenylpropenes, and “others”. In addition, they may contain… Read more »

Essential oils of culinary herbs and spices display agonist and antagonist activities at human aryl hydrocarbon receptor AhR

Bartoňková I, Dvořák Z Food Chemistry & Toxicology ABSTRACT: Essential oils (EOs) of culinary herbs and spices are used to flavor, color and preserve foods and drinks. Dietary intake of EOs is significant, deserving an attention of toxicologists. We examined the effects of 31 EOs of culinary herbs and spices on the transcriptional activity of human… Read more »

The effect of fennel essential oil in combination with antibiotics on Staphylococcus aureus strains isolated from carriers

Kwiatkowski P, Mnichowska-Polanowska M, Pruss A, Masiuk H, Dzięcioł M, Giedrys-Kalemba S, Sienkiewicz M Burns, 2017 ABSTRACT: An increase in the number of staphylococcal infections and carriers among medical staff has forced us to seek more and more effective antibacterial agents. Bacteria from the Staphylococcus genus possessing different mechanisms of resistance are the cause of… Read more »

Synergistic interaction of ten essential oils against Haemonchus contortus in vitro

Katiki LM, Barbieri AME, Araujo RC, Veríssimo CJ, Louvandini H, Ferreira JFS Veterinary Parasitology, 2017 ABSTRACT: Anthelmintic resistance in sheep gastrointestinal nematodes is a worldwide problem. Multi-drug resistant haemonchosis is the most serious impediment for small ruminant systems, and there are no new drug candidates currently under development. Molecules from natural sources have demonstrated anthelmintic… Read more »

Cytotoxicity of the Essential Oil of Fennel (Foeniculum vulgare) from Tajikistan

Sharopov F, Valiev A, Satyal P, Gulmurodov I, Yusufi S, Setzer WN, Wink M Foods, 2017 ABSTRACT: The essential oil of fennel (Foeniculum vulgare) is rich in lipophilic secondary metabolites, which can easily cross cell membranes by free diffusion. Several constituents of the oil carry reactive carbonyl groups in their ring structures. Carbonyl groups can… Read more »

Anethole Inhibits The Proliferation Of Human Prostate Cancer Cells Via Induction Of Cell Cycle Arrest And Apoptosis

Elkady AI Anti-Cancer Agents in Medicinal Chemistry, 2017 ABSTRACT: BACKGROUND: Prostate cancer-associated mortality is increasing at an alarming rate, which highlights the inevitability for unearthing novel agent for the management of this disease. Anethole, a major constituent of Foeniculum vulgare (fennel) essential oil, is widely used in folk medicine; it possesses anti-oxidant, anti-inflammatory, anti-proliferative and tumoricidal potentialities…. Read more »

Antitumor phenylpropanoids found in essential oils

Carvalho AA, Andrade LN, de Sousa ÉB, de Sousa DP Biomed Research International, 2015  ABSTRACT: The search for new bioactive substances with anticancer activity and the understanding of their mechanisms of action are high-priorities in the research effort toward more effective treatments for cancer. The phenylpropanoids are natural products found in many aromatic and medicinal… Read more »

Anethole restores delayed gastric emptying and impaired gastric accommodation in rodents

Asano T, Aida S, Suemasu S, Mizushima T Biochemical and biophysical research communications, 2016 ABSTRACT: Functional dyspepsia (FD), a functional gastrointestinal disorder, is characterized by persistent or recurrent postprandial upper abdominal discomfort and epigastric pain. The high prevalence of FD and associated healthcare costs suggests that treatment of this condition by methods other than prescribed… Read more »