Nigella damascena L. essential oil and its main constituents, damascenine and β-elemene modulate inflammatory response of human neutrophils ex vivo

Sieniawska E, Michel P, Mroczek T, Granica S, Skalicka-woźniak K Food and Chemical Toxicology, 2019 ABSTRACT: Nigella damascena L belongs to Ranunculaceae family and is mentioned in Eastern traditional medicine for the treatment of high temperatures, regulation of menstruation or catarrhal affections. The anti-inflammatory activity of compounds present in the essential oil obtained from seeds… Read more »

Expression of P53, BAX, and BCL-2 in human malignant melanoma and squamous cell carcinoma cells after tea tree oil treatment in vitro

Ramadan MA, Shawkey AE, Rabeh MA, Abdellatif AO Cytotechnology, 2019 ABSTRACT: Tea tree oil (TTO) is an essential oil obtained by steam distillation from the leaves of Melaleuca alternifolia (Myrtaceae). This oil has traditionally been used for the treatment of various skin infections. The present study aimed to investigate the cytotoxic effects of TTO against… Read more »

Camphor white oil induces tumor regression through cytotoxic T cell-dependent mechanisms

Moayedi Y, Greenberg SA, Jenkins BA, Marshall KL, Dimitrov LV, Nelson AM, Owens DM, Lumpkin EA Molecular Carcinogenesis, 2018 ABSTRACT: Bioactive derivatives from the camphor laurel tree, Cinnamomum camphora, are posited to exhibit chemopreventive properties but the efficacy and mechanism of these natural products are not fully understood. We tested an essential-oil derivative, camphor white… Read more »

Potential anti-inflammatory and antioxidant effects of Citrus aurantium essential oil against carbon tetrachloride-mediated hepatotoxicity: A biochemical, molecular and histopathological changes in adult rats

Ben Hsouna A, Gargouri M, Dhifi W, Ben Saad R, Sayahi N, Mnif W, Saibi W Environmental Toxicology, 2019 ABSTRACT: The present study aimed (1) to investigate the chemical composition as well as the anti-inflammatory properties and in vitro antioxidant activity of Citrus aurantium peel essential oil (pEOCa) and (2) to evaluate its potential effect… Read more »

Protective effect of essential oil from Citrus limon against aspirin-induced toxicity in rats

Bouzenna H, Samout N, Dhibi S, Mbarki S, Akermi S, Khdhiri A, Elfeki A, Hfaiedh N Human & Experimental Toxicology, 2018 ABSTRACT: The present study is planned to examine the antioxidant activity (AA) and the protective effect of the essential oil of Citrus limon (EOC) against aspirin-induced histopathological changes in the brain, lung, and intestine… Read more »

Effectiveness of topical administration of Anethum graveolens essential oil on MRSA-infected wounds

Manzuoerh R, Farahpour MR, Oryan A, Sonboli A Biomedicine and Pharmacotherapy, 2019 ABSTRACT: Medicinal plants are conventionally used for wound healing, but their action mechanisms are still unknown. The present study evaluated the effect of topical administration of ointment containing dill (Anethum graveolens) essential oil (DEO) in the management of apoptosis and cell proliferation during… Read more »

Evaluation of the possible use of genus Mentha derived essential oils in the prevention of SENLAT syndrome caused by Rickettsia slovaca

Štefanidesová K, Špitalská E, Csicsay F, Friedländerová V, Šáner A, Škultéty Ľ Journal of Ethnopharmacology, 2018 ABSTRACT: ETHNOPHARMACOLOGICAL RELEVANCE: Essential oils and essential oil bearing medicinal and culinary plants have a long tradition of being used to combat infection, treat various conditions, and promote and restore health. Mint oils are traditionally applied to repel insects… Read more »

Chemoprevention of Colorectal Cancer by Dietary Compounds

Costea T, Hudiță A, Ciolac OA, Gălățeanu B, Ginghină O, Costache M, Ganea C, Mocanu MM International Journal of Molecular Sciences, 2018 ABSTRACT: Colorectal cancer is one of the leading causes of death, and the third most diagnosed type of cancer, worldwide. It is most common amongst men and women over 50 years old. Risk… Read more »

Effect of a Toothpaste/Mouthwash Containing Carica Papaya Leaf Extract on Interdental Gingival Bleeding: A Randomized Controlled Trial

Saliasi I, Llodra JC, Bravo M, Tramini P, Dussart C, Viennot S, Carrouel F International Journal of Environmental Research and Public Health, 2018 ABSTRACT: Clinical research on herbal-based dentifrice +/- mouth rinse products is very limited compared with the plethora of research on conventional oral care products under normal oral hygiene conditions. The aim of… Read more »

Toxicity of Melaleuca alternifolia essential oil to the mitochondrion and NAD/NADH dehydrogenase in Tribolium confusum

Liao M, Yang QQ, Xiao JJ, Huang Y, Zhou LJ, Hua RM, Cao HQ PeerJ, 2018 ABSTRACT: BACKGROUND: In our previous study, Melaleuca alternifolia essential oil (EO) was considered to have an insecticidal effect by acting on the mitochondrial respiratory chain in insects. However, the mode of action is not fully understood. METHODS: In this… Read more »