Nervous System

This system includes the brain, spinal cord, sensory receptors and peripheral nerves. Disorders include strokes, dementia, Alzheimer’s, Huntington’s, Parkinson’s, ADHD, epilepsy, anxiety disorders, mood disorders and stress.

Inhaled linalool-induced sedation in mice

Linck VM, da Silva AL, Figueiró M, Piato AL, Herrmann AP, Dupont Birck F, Caramão EB, Nunes DS, Moreno PR, Elisabetsky E Phytomedicine : international journal of phytotherapy and phytopharmacology ABSTRACT: Linalool is a monoterpene often found as a major component of essential oils obtained from aromatic plant species, many of which are used in… Read more »

Diterpenes: Advances in Neurobiological Drug Research

Islam MT, da Silva CB, de Alencar MV, Paz MF, Almeida FR, Melo-Cavalcante AA Phytotherapy research, 2016 ABSTRACT: A significant number of studies have been performed with diterpene effect on the brain. Our study aims to make a systematic revision on them. The initial purpose of this review was to screen diterpenes with neurological activity,… Read more »

Essential oils from Apiaceae as valuable resources in neurological disorders: Foeniculi vulgare aetheroleum

Cioancaa O, Hancianua M, Mirceab C, Trifana A, Hritcuc L Industrial Crops and Products, 2016 ABSTRACT: Used as a spice and to improve the palatability of different meat and vegetable dishes, common fennel, Foeniculum vulgare Mill. (Apiaceae), was a traditional remedy for the relief of spasms and colic due to gas accumulation, to stimulate gastrointestinal… Read more »

Thymol, a constituent of thyme essential oil, is a positive allosteric modulator of human GABA(A) receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster

Priestley CM, Williamson EM, Wafford KA, Sattelle DB British journal of pharmacology, 2003 ABSTRACT: The GABA-modulating and GABA-mimetic activities of the monoterpenoid thymol were explored on human GABAA and Drosophila melanogaster homomeric RDLac GABA receptors expressed in Xenopus laevis oocytes, voltage-clamped at -60 mV. The site of action of thymol was also investigated. Thymol, 1-100… Read more »

Anticonvulsant activity of β-caryophyllene against pentylenetetrazol-induced seizures

de Oliveira CC, de Oliveira CV, Grigoletto J, Ribeiro LR, Funck VR, Grauncke AC, de Souza TL, Souto NS, Furian AF, Menezes IR, Oliveira MS Epilepsy & behavior : E&B, 2016 ABSTRACT: Increasing evidence suggests that plant-derived extracts and their isolated components are useful for treatment of seizures and, hence, constitute a valuable source of… Read more »

Chemistry and Pharmacology of Citrus sinensis

Favela-Hernández JM, González-Santiago O, Ramírez-Cabrera MA, Esquivel-Ferriño PC, Camacho-Corona Mdel R Molecules, 2016 ABSTRACT: Presently the search for new drugs from natural resources is of growing interest to the pharmaceutical industry. Natural products have been the source of new drugs since ancient times. Plants are a good source of secondary metabolites which have been found… Read more »

Antioxidant activity of linalool in patients with carpal tunnel syndrome

Seol GH, Kang P, Lee HS, Seol GH BMC neurology, 2016 ABSTRACT: BACKGROUND: Carpal tunnel syndrome (CTS) is a common peripheral neuropathy and ischemic-reperfusion injury. Oxidative stress is considered a major cause of CTS. Linalool, a component of essential oils, has antioxidant activity. This study was designed to determine the effects of linalool inhalation on… Read more »

Combined non-adaptive light and smell stimuli lowered blood pressure, reduced heart rate and reduced negative affect

Dong S, Jacob TJ Physiology & behavior, 2016 ABSTRACT: Bright light therapy has been shown to have a positive impact on seasonal affective disorder (SAD), depression and anxiety. Smell has also has been shown to have effects on mood, stress, anxiety and depression. The objective of this study was to investigate the effect of the… Read more »

The Effects of Aroma Foot Massage on Blood Pressure and Anxiety in Japanese Community-Dwelling Men and Women: A Crossover Randomized Controlled Trial

Eguchi E, Funakubo N, Tomooka K, Ohira T, Ogino K, Tanigawa T PloS one, 2016 ABSTRACT: OBJECTIVES: The aim of this study was to investigate the effects of aroma foot massage on blood pressure, anxiety, and health-related quality of life (QOL) in Japanese community-dwelling men and women using a crossover randomized controlled trial. METHODS: Fifty-seven… Read more »

Anxiolytic Effect of Citrus aurantium L. on Patients with Chronic Myeloid Leukemia

Pimenta FC, Alves MF, Pimenta MB, Melo SA, Almeida AA, Leite JR, Pordeus LC, Diniz Mde F, Almeida RN Phytotherapy research : PTR, 2016 ABSTRACT: The bone marrow aspiration procedure is used in hematological diseases and consists of a painful, invasive procedure causing anxiety-associated symptoms. The present study assessed the effect of Citrus aurantium L…. Read more »