Patchouli Alcohol

  • Backbone: Sesquiterpene
  • Functional Group: Alcohol

Essential Oil Compound, Patchouli Alcohol, Represses Tumor Formation in Vivo and Causes G1 Arrest by Downregulating β-catenin Transcriptional Activity in Colon Cancer Cells

Lee J, Lee SH Current Developments in Nutrition, 2019 ABSTRACT: OBJECTIVES: Patchouli alcohol is one of the abundant compounds isolated from essential oil of Pogostemon cablin and shows anti-inflammatory, anti-obese and anti-cancer activities. The current study was designed to investigate if treatment of patchouli alcohol exhibits tumor suppressive activity in colon cancer mouse model and… Read more »

Honeysuckle essential oil as a potential source of ecofriendly larvicides for mosquito control

Muturi EJ, Doll K, Berhow M, Flor-weiler LB, Rooney AP Pest Management Science, 2019 ABSTRACT: BACKGROUND: Some plant essential oils have insecticidal properties against mosquitoes and can be harnessed as ecofriendly tools for mosquito control. We conducted bioassays to determine the toxicity of Italian honeysuckle (Lonicera caprifolium) essential oil and its fractions against larvae of… Read more »

Amelioration of methylmercury induced neural damage by essential oil of Selinum vaginatum (Edgew) C. B. Clarke

Thiagarajan K, Gamit N, Mandal S, Ayyathan DM, Chandrasekaran R Pakistan Journal of Pharmaceutical Sciences, 2018 ABSTRACT: Methylmercury (MeHg), an organometallic contaminant is a well spotted cause for a series of disorders, especially in the central nervous system. As there is no proper treatment, Selinum vaginatum (Edgew) C. B. Clarke, a traditional medicinal plant, is… Read more »

Patchouli oil ameliorates acute colitis: A targeted metabolite analysis of 2,4,6-trinitrobenzenesulfonic acid-induced rats

Yu X, Yang G, Jiang H, Lin S, Liu Y, Zhang X, Zeng H, Su Z, Huang S, Shen L, Zhang X Experimental and Therapeutic Medicine, 2017 ABSTRACT: The incidence of inflammatory bowel disease (IBD), characterized by chronic, relapsing intestinal inflammation, has continually increased in recent years. A previous study by our group identified five… Read more »

Anti-nociceptive effect of patchouli alcohol: Involving attenuation of cyclooxygenase 2 and modulation of mu-opioid receptor

Yu X, Wang XP, Yan XJ, Jiang JF, Lei F, Xing DM, Guo YY, Du LJ Chinese Journal of Integrated Medicine, 2017 OBJECTIVE: To explore the anti-nociceptive effect of patchouli alcohol (PA), the essential oil isolated from Pogostemon cablin (Blanco) Bent, and determine the mechanism in molecular levels. METHODS: The acetic acid-induced writhing test and formalin-induced plantar… Read more »