Melaleuca quinquenervia essential oil inhibits α-melanocyte-stimulating hormone-induced melanin production and oxidative stress in B16 melanoma cells

Chao WW, Su CC, Peng HY, Chou ST Phytomedicine, 2017 BACKGROUND: Essential oils are odorous, volatile products of plant secondary metabolism, which are found in many leaves and stems. They show important biological activities, which account for the development of aromatherapy used in complementary and alternative medicine. The essential oil extracted from Melaleuca quinquenervia (Cav.) S.T. Blake (paperbark)… Read more »

Intranasal co-administration of 1,8-cineole with influenza vaccine provide cross-protection against influenza virus infection

Li Y, Xu YL, Lai YN, Liao SH, Liu N, Xu PP Phytomedicine, 2017 BACKGROUND: Vaccination is the most efficient means for protection against influenza. However, the various vaccines have low efficacy to protect against pandemic strains because of antigenic drift and recombination of influenza virus. Adjuvant therapy is one of the attempts to improve… Read more »

Susceptibility of herpes simplex virus type 1 to monoterpenes thymol, carvacrol, p-cymene and essential oils of Sinapis arvensis L., Lallemantia royleana Benth. and Pulicaria vulgaris Gaertn

Sharifi-Rad J, Salehi B, Schnitzler P, Ayatollahi SA, Kobarfard F, Fathi M, Eisazadeh M, Sharifi-Rad M Cellular and Molecular Biology, 2017 ABSTRACT: In recent years, with increased the prevalence of viral infections and having no specific for  their treatment  and also the continuous appearance of resistant viral strains, the finding of novel antiviral agents is… Read more »

Genomic Analysis of Terpene Synthase Family and Functional Characterization of Seven Sesquiterpene Synthases from Citrus sinensis

Alquézar B, Rodríguez A, de la Peña M, Peña L Frontiers in Plant Science, 2017 ABSTRACT: Citrus aroma and flavor, chief traits of fruit quality, are derived from their high content in essential oils of most plant tissues, including leaves, stems, flowers, and fruits. Accumulated in secretory cavities, most components of these oils are volatile terpenes. They… Read more »

Anti-inflammatory effect of essential oil from Citrus aurantium L. var. amara Engl

Shen CY, Jiang JG, Ou-Yang Q, Zhu W Journal of Agricultural and Food Chemistry, 2017 ABSTRACT: Essential oil has been popularly used as an alternative for the treatment of inflammation. The bioactivities of essential oil from blossoms of Citrus aurantium L. var. amara Engl (CAVAO) showed greater anti-inflammation potential than that of antioxidant, anticancer, and 3T3-L1 proliferation inhibition…. Read more »

Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus Aureus: Importance in Compounding for Wound Care

Guimarães AL, Cunha EA, Matias FO, Garcia PG, Danopoulos P, Swikidisa R, Pinheiro VA, Nogueira RJ International Journal of Pharmaceutical Compounding, 2016 ABSTRACT: The Amazon rainforest is the largest reserve of natural products in the world. Its rich biodiversity of medicinal plants has been utilized by local populations for hundreds of years for the prevention… Read more »

Anti-Inflammatory and Antioxidant Actions of Copaiba Oil Are Related to Liver Cell Modifications in Arthritic Rats

Castro Ghizoni CV, Arssufi Ames AP, Lameira OA, Bersani Amado CA, Sá Nakanishi AB, Bracht L, Marçal Natali MR, Peralta RM, Bracht A, Comar JF Journal of Cellular Biochemistry, 2017 ABSTRACT: The present study investigated the action of copaiba oil (Copaifera reticulata) on the systemic inflammation, oxidative status, and liver cell metabolism of rats with adjuvant-induced arthritis…. Read more »

Effects of Copaiba Oil Topical Administration on Oral Wound Healing

Wagner VP, Webber LP, Ortiz L, Rados PV, Meurer L, Lameira OA, Lima RR, Martins MD Phytotherapy Research, 2017 ABSTRACT: The effects of topical copaiba oil extract and topical corticosteroid were assessed on oral wound healing in an in vivo model using 96 male Wistar rats. Traumatic ulcers were caused in the dorsum of the tongue using… Read more »

Anti-inflammatory Effect from a Hydrogel Containing Nanoemulsified Copaiba oil (Copaifera multijuga Hayne)

Lucca LG, de Matos SP, Kreutz T, Teixeira HF, Veiga VF Jr, de Araújo BV, Limberger RP, Koester LS AAPS PharmSciTech, 2017 ABSTRACT: Copaiba oil is used as a popular medicine in the Amazonian forest region, especially due to its anti-inflammatory properties. In this paper, we describe the formulation of hydrogel containing copaiba oil nanoemulsions (with positive and… Read more »

Copaiba oil: chemical composition and influence on in vitro cutaneous permeability of Celecoxib.

Quiñones OG, Abranches RP, Nakamura MJ, de Souza Ramos MF, Pierre MBR Current Drug Delivery, 2017 BACKGROUND: Use of topical or transdermal administration of Celecoxib (Cxb) is an interesting strategy in cutaneous treatments since it reduces or avoids side effects of the oral route. However, Cxb´s high lipophilicity and the stratum corneum (SC) barrier impair… Read more »