Terpenes from essential oils and hydrolate of Teucrium alopecurus triggered apoptotic events dependent on caspases activation and PARP cleavage in human colon cancer cells through decreased protein expressions

Guesmi F, Tyagi AK, Prasad S, Landoulsi A Oncotarget, 2018 ABSTRACT: This study focused on characterizing the Hydrophobic and Hydrophilic fractions of Teucrium alopecurus in the context of cancer prevention and therapy. The goal was also to elucidate the molecular mechanisms involved and to determine its efficacy against cancer by triggering apoptosis and suppressing tumorigenesis… Read more »

Antibacterial activity of traditional spices against lower respiratory tract pathogens: combinatorial effects of Trachyspermum ammi essential oil with conventional antibiotics

Grădinaru AC, Trifan A, Şpac A, Brebu M, Miron A, Aprotosoaie AC Letters in Applied Microbiology, 2018 ABSTRACT: The aim of this study was to investigate the effects of ajowan essential oil (AjEO)/thymol and antibiotics combinations against three standard strains and six resistant clinical isolates of major respiratory bacteria (Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus… Read more »

Plant-Derived Products as Antibacterial and Antifungal Agents in Human Health Care

Kokoska L, Kloucek P, Leuner O, Novy P Current Medicinal Chemistry, 2018 ABSTRACT: A number of papers reporting antimicrobial properties of extracts, essential oils, resins and various classes of compounds isolated from higher plants has been published in recent years; however, a comprehensive analysis of plant-derived antimicrobial agents currently applied in practice for improvement of… Read more »

Anti-cancer effects of Rhizoma Curcumae against doxorubicin-resistant breast cancer cells

Zhong Z, Yu H, Wang S, Wang Y, Cui L Chinese Medicine, 2018 ABSTRACT: BACKGROUND: Chemotherapy is a primary approach in cancer treatment after routine surgery. However, chemo-resistance tends to occur with chemotherapy in clinic, resulting in poor prognosis and recurrence. Nowadays, Chinese medicine may shed light on design of new therapeutic modes to overcome… Read more »

The use of mouthwash containing essential oils (LISTERINE®) to improve oral health: A systematic review

Alshehri FA The Saudi Dental Journal, 2018 ABSTRACT: BACKGROUND: Standard recommendations to maintain daily oral hygiene include tooth brushing and interdental cleaning. Evidence from literature indicates that using a mouthrinse as an adjunct provides benefit beyond mechanical methods. The objective of this article was to evaluate the short- and long-term effect of a mouthwash containing… Read more »

Ovicidal effect of essential oils from Zingiberaceae plants and Eucalytus globulus on eggs of head lice, Pediculus humanus capitis De Geer

Soonwera M, Wongnet O, Sittichok S Phytomedicine, 2018 ABSTRACT: BACKGROUND: Head lice infestation is an important public health problem worldwide. Chemical pediculicides have lost their efficacy because lice have developed resistance to them. Therefore, alternative pediculicides such as essential oils and herbal products have been proposed for treating head lice infestation. STUDY DESIGN: To determine… Read more »

Synergistic interaction of β-caryophyllene with aromadendrene oxide 2 and phytol induces apoptosis on skin epidermoid cancer cells

Pavithra PS, Mehta A, Verma RS Phytomedicine, 2018 ABSTRACT: BACKGROUND: Pamburus missionis (Wight) Swingle (Rutaceae) is traditionally used in the treatment of swellings, chronic rheumatism, paralysis and puerperal diseases. In a previous study the authors demonstrated apoptotic activity of Pamburus missionis essential oil (EO) on A431 and HaCaT cells. The major components of EO were… Read more »

Essential Oil as a Potential Anti-Acne Topical Nanoemulsion-In Vitro and In Vivo Study

Taleb MH, Abdeltawab NF, Shamma RN, Abdelgayed SS, Mohamed SS, Farag MA, Ramadan MA Molecules, 2018 ABSTRACT: Antibiotics are often prescribed in acne treatment; however, Propionibacterium acnes and Staphylococcus epidermidis, the two of the major acne-associated bacteria, developed antibiotic resistance. Essential oils (EOs) present a natural, safe, efficacious and multifunctional alternative treatment. This study aimed… Read more »

AMPK Activation Mediated by Hinokitiol Inhibits Adipogenic Differentiation of Mesenchymal Stem Cells through Autophagy Flux

Lee JH, Jeong JK, Park SY International Journal of Endocrinology, 2018 ABSTRACT: BACKGROUND AND PURPOSE: Hinokitiol, a natural monopenoid present in the essential oil of Calocedrus formosana heartwood, exerts potent anticancer, anti-inflammatory, antibacterial, and neuroprotective effects on various cells. However, the antiobesity effect of hinokitiol on adipocytes is unclear. EXPERIMENTAL APPROACH: In this study, we… Read more »