Reproductive System

This system includes the sex organs and secondary sex characters. Disorders include endometriosis, STDs, erectile dysfunction, menstrual cramps, heavy periods, menopause, infertility, and sexual arousal disorders.

Cymbopogon citratus and Cymbopogon giganteus essential oils have cytotoxic effects on tumor cell cultures. Identification of citral as a new putative anti-proliferative molecule

Bayala B, Bassole IHN, Maqdasy S, Baron S, Simpore J, Lobaccaro JA Biochimie, 2018 ABSTRACT: Cymbopogon species are used as traditional remedies in Burkina Faso for treating several diseases. We aimed to study the effects of their essential oils on cancer cell lines. For that purpose, Cymbopogon citratus (DC.) Stapf. and Cymbopogon giganteus Chiov. were… Read more »

Role of Essential Oil of Mentha Spicata (Spearmint) in Addressing Reverse Hormonal and Folliculogenesis Disturbances in a Polycystic Ovarian Syndrome in a Rat Model

Sadeghi Ataabadi M, Alaee S, Bagheri MJ, Bahmanpoor S Advanced Pharmaceutical Bulletin, 2017 ABSTRACT: Purpose: Given the antiandrogenic effects of spearmint, in this study we evaluated the effects of its essential oil on polycystic ovarian syndrome in a rat model. Methods: Female rats were treated as follows: Control, normal rats which received 150 mg/kg spearmint… Read more »

Involvement of Bax and Bcl-2 in Induction of Apoptosis by Essential Oils of Three Lebanese Salvia Species in Human Prostate Cancer Cells

Russo A, Cardile V, Graziano ACE, Avola R, Bruno M, Rigano D International Journal of Molecular Sciences, 2018 ABSTRACT: Prostate cancer is one of the most common forms of cancer in men, and research to find more effective and less toxic drugs has become necessary. In the frame of our ongoing program on traditionally used… Read more »

Changes in salivary oxytocin after inhalation of clary sage essential oil scent in term-pregnant women: a feasibility pilot study

Tadokoro Y, Horiuchi S, Takahata K, Shuo T, Sawano E, Shinohara K BMC Research Notes, 2017 OBJECTIVES: This pilot study using a quasi-experimental design was conducted to evaluate the feasibility (i.e., limited efficacy, practicality, and acceptability) of our intervention protocol involving inhalation of the scent of clary sage essential oil by pregnant women and measurement of their… Read more »

Thymbra capitata (L.) Cav. and Rosmarinus officinalis (L.) Essential Oils: In Vitro Effects and Toxicity on Swine Spermatozoa

Elmi A, Ventrella D, Barone F, Filippini G, Benvenuti S, Pisi A, Scozzoli M, Bacci ML Molecules, 2017 ABSTRACT: Essential oils possess a variety of biological properties (i.e., antioxidant, antibacterial, and cytotoxic) that could possibly be applied in reproductive medicine, but their effects on spermatozoa are still partially unknown. The aim of the study was to… Read more »

Frankincense, pine needle and geranium essential oils suppress tumor progression through the regulation of the AMPK/mTOR pathway in breast cancer

Ren P, Ren X, Cheng L, Xu L Oncology reports, 2017 ABSTRACT: BC (BC), as the most common malignancy in women worldwide, is associated with high morbidity and mortality. However, chemoresistance and toxicity are the main causes that limit the success of treatment in aggressive BC cases. Thus, there is a vital need to identify and… Read more »

Genotoxicity of carbon tetrachloride and the protective role of essential oil of Salvia officinalis L. in mice using chromosomal aberration, micronuclei formation, and comet assay

Diab KA, Fahmy MA, Hassan ZM, Hassan EM, Salama AB, Omara EA Environmental Science and Pollution Research, 2017 ABSTRACT: The present work was conducted to evaluate the genotoxic effect of carbon tetrachloride (CCl4) in mouse bone marrow and male germ cells. The safety and the modulating activity of sage (Salvia officinalis L.) essential oil (SEO) against the… Read more »

Menthol evokes Ca2+ signals and induces oxidative stress independently of the presence of TRPM8 (menthol) receptor in cancer cells.

Nazıroğlu M, Blum W, Jósvay K, Çiğ B, Henzi T, Oláh Z, Vizler C, Schwaller B, Pecze L Redox Biology, 2017 ABSTRACT: Menthol is a naturally occurring monoterpene alcohol possessing remarkable biological properties including antipruritic, analgesic, antiseptic, anti-inflammatory and cooling effects. Here, we examined the menthol-evoked Ca2+ signals in breast and prostate cancer cell lines. The… Read more »

δ-Cadinene inhibits the growth of ovarian cancer cells via caspase-dependent apoptosis and cell cycle arrest

Hui LM, Zhao GD, Zhao JJ International Journal of Clinical and Experimental Pathology, 2015 ABSTRACT: Ovarian cancer is one of the most common causes of mortality among all cancers in females and is the primary cause of mortality from gynecological malignancies. The objective of the current research work was to evaluate a naturally occurring sesquiterpene-δ-Cadinene for… Read more »

A Review of the Composition of the Essential Oils and Biological Activities of Angelica Species

Sowndhararajan K, Deepa P, Kim M, Park SJ, Kim S Scientia pharmaceutica, 2017 ASBTRACT: A number of Angelica species have been used in traditional systems of medicine to treat many ailments. Especially, essential oils (EOs) from the Angelica species have been used for the treatment of various health problems, including malaria, gynecological diseases, fever, anemia, and arthritis. EOs are complex mixtures… Read more »