Han X, Parker TL Cogent Medicine, 2017 ABSTRACT: Cardamom (Elettaria cardamomum) essential oil (CEO) is popular in skin care, although no studies have reported its biological activity in human skin cells. We studied its effect on 17 protein biomarkers closely related to inflammation, immune responses, and tissue remodeling using a dermal fibroblast cell culture system… Read more »
Arborvitae (Thuja plicata) essential oil significantly inhibited critical inflammation- and tissue remodeling-related proteins and genes in human dermal fibroblasts
Han X, Parker TL Biochimie Open, 2017 ABSTRACT: Arborvitae (Thuja plicata) essential oil (AEO) is becoming increasingly popular in skincare, although its biological activity in human skin cells has not been investigated. Therefore, we sought to study AEO’s effect on 17 important protein biomarkers that are closely related to inflammation and tissue remodeling by using… Read more »
Bergamot (Citrus bergamia) Essential Oil Inhalation Improves Positive Feelings in the Waiting Room of a Mental Health Treatment Center: A Pilot Study
Han X, Gibson J, Eggett DL, Parker TL Phytotherapy Research, 2017 ABSTRACT: Mental health issues have been increasingly recognized as public health problems globally. Their burden is projected to increase over the next several decades. Additional therapies for mental problems are in urgent need worldwide due to the limitations and costs of existing healthcare approaches…. Read more »
Anti-inflammatory activity of clove (Eugenia caryophyllata) essential oil in human dermal fibroblasts
Han X, Parker TL Pharmaceutical Biology, 2017 CONTEXT: Clove (Eugenia caryophyllata Thunb. [Myrtaceae]) essential oil (CEO) has been shown to possess antimicrobial, antifungal, antiviral, antioxidant, anti-inflammatory and anticancer properties. However, few studies have focused on its topical use. OBJECTIVE: We investigated the biological activity of a commercially available CEO in a human skin disease model…. Read more »
Antiinflammatory Activity of Cinnamon (Cinnamomum zeylanicum) Bark Essential Oil in a Human Skin Disease Model
Han X, Parker TL Phytotherapy Research, 2017 ABSTRACT: The effect of cinnamon (Cinnamomum zeylanicum) bark essential oil (CBEO) on human skin cells has not been elucidated. Therefore, we investigated the activity of a commercially available CBEO in a validated human dermal fibroblast system, a model of chronic inflammation and fibrosis. We first evaluated the impact… Read more »
Preclinical development and clinical use of perillyl alcohol for chemoprevention and cancer therapy
Chen TC, Fonseca CO, Schönthal AH American Journal of Cancer Research, 2015 ABSTRACT: Perillyl alcohol (POH) is a naturally occurring dietary monoterpene isolated from the essential oils of lavender, peppermint, and other plants. Medical interest in this compound was generated by research findings showing that POH was able to inhibit the growth of tumor cells… Read more »
Essential oils and their constituents as anticancer agents: a mechanistic view
Gautam N, Mantha AK, Mittal S BioMed Research International, 2014 ABSTRACT: Exploring natural plant products as an option to find new chemical entities as anticancer agents is one of the fastest growing areas of research. Recently, in the last decade, essential oils (EOs) have been under study for their use in cancer therapy and the… Read more »
Antitumor phenylpropanoids found in essential oils
Carvalho AA, Andrade LN, de Sousa ÉB, de Sousa DP Biomed Research International, 2015 ABSTRACT: The search for new bioactive substances with anticancer activity and the understanding of their mechanisms of action are high-priorities in the research effort toward more effective treatments for cancer. The phenylpropanoids are natural products found in many aromatic and medicinal… Read more »
Effectiveness of Silexan oral lavender essential oil compared to inhaled lavender essential oil aromatherapy on sleep in adults: a systematic review protocol
Greenberg MJ, Slyer JT JBI Database of Systematic Reviews and Implementation Reports, 2017 ABSTRACT: The objective of this review is to identify the effectiveness of Silexan oral lavender essential oil compared to inhaled lavender essential oil aromatherapy on sleep latency, sleep duration, sleep quality, disturbed sleep and anxiety in adult patients. CITATION: Greenberg MJ, Slyer… Read more »
Genetic diversity and metabolic profile of Salvia officinalis populations: implications for advanced breeding strategies
Sarrou E, Ganopoulos I, Xanthopoulou A, Masuero D, Martens S, Madesis P, Mavromatis A, Chatzopoulou P Planta, 2017 ABSTRACT: MAIN CONCLUSION: As a result of this work, we were able to characterize seven indigenous to Greece Salvia officinalis populations using genetic and metabolomic tools. These tools can be used to select the most promising genotypes, capable to… Read more »