Gautam N, Mantha AK, Mittal S BioMed Research International, 2014 ABSTRACT: Exploring natural plant products as an option to find new chemical entities as anticancer agents is one of the fastest growing areas of research. Recently, in the last decade, essential oils (EOs) have been under study for their use in cancer therapy and the… Read more »
Thymol
- Backbone: Monoterpene
- Functional Group: Phenol
Thymol reduces oxidative stress, aortic intimal thickening, and inflammation-related gene expression in hyperlipidemic rabbits
Yua YM, Chaob TY, Changb WC, Changb MJ, Leea MF Journal of Food and Drug Analysis, 2016 ABSTRACT: Atherosclerosis plays a key role in the development of cardiovascular diseases, and is often associated with oxidative stress and local inflammation. Thymol, a major polyphenolic compound in thyme, exhibits antioxidant and anti-inflammatory properties. In this study, we… Read more »
The protective effects of carvacrol and thymol against paracetamol-induced toxicity on human hepatocellular carcinoma cell lines (HepG2)
Palabiyik SS, Karakus E, Halici Z, Cadirci E, Bayir Y, Ayaz G, Cinar I Human & experimental toxicology, 2016 ABSTRACT: Acetaminophen (APAP) overdose could induce liver damage and lead to acute liver failure. The treatment of APAP overdoses could be improved by new therapeutic strategies. Thymus spp., which has many beneficial effects and has been… Read more »
Chitin-Induced Airway Epithelial Cell Innate Immune Responses Are Inhibited by Carvacrol/Thymol
Khosravi AR, Erle DJ PloS one, 2016 ABSTRACT: Chitin is produced in large amounts by fungi, insects, and other organisms and has been implicated in the pathogenesis of asthma. Airway epithelial cells are in direct contact with environmental particles and serve as the first line of defense against inhaled allergens and pathogens. The potential contributions… Read more »
Thymol, a constituent of thyme essential oil, is a positive allosteric modulator of human GABA(A) receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster
Priestley CM, Williamson EM, Wafford KA, Sattelle DB British journal of pharmacology, 2003 ABSTRACT: The GABA-modulating and GABA-mimetic activities of the monoterpenoid thymol were explored on human GABAA and Drosophila melanogaster homomeric RDLac GABA receptors expressed in Xenopus laevis oocytes, voltage-clamped at -60 mV. The site of action of thymol was also investigated. Thymol, 1-100… Read more »
Plant essential oils for pest and disease management
Murray B Isman Crop Protection, 2000 ABSTRACT: Certain essential plant oils, widely used as fragrances and flavors in the perfume and food industries, have long been reputed to repel insects. Recent investigations in several countries confirm that some plant essential oils not only repel insects, but have contact and fumigant insecticidal actions against specific pests,… Read more »
Antibacterial and antifungal activities of thymol: A brief review of the literature
Marchesea A, Orhanb IE, Dagliac M, Barbieria R, Lorenzoc AD, Nabavid SF, Gortzie O, Izadif M, Nabavid SM Food Chemistry, 2016 ABSTRACT: Thymol (2-isopropyl-5-methylphenol) is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family (Thymus, Ocimum,Origanum, and Monarda genera), and other plants such as those belonging to the… Read more »
In-vitro effects of Thymus munbyanus essential oil and thymol on human sperm motility and function
Chikhoune A, Stouvenel L, Iguer-Ouada M, Hazzit M, Schmitt A, Lorès P, Wolf JP, Aissat K, Auger J, Vaiman D, Touré A Reproductive biomedicine online, 2015 ABSTRACT: Traditional medicine has been used worldwide for centuries to cure or prevent disease and for male or female contraception. Only a few studies have directly investigated the effects… Read more »
Larvicidal potential of carvacrol and terpinen-4-ol from the essential oil of Origanum vulgare (Lamiaceae) against Anopheles stephensi, Anopheles subpictus, Culex quinquefasciatus and Culex tritaeniorhynchus (Diptera: Culicidae)
Govindarajan M, Rajeswary M, Hoti SL, Benelli G Research in veterinary science, 2016 ABSTRACT: Mosquito-borne diseases represent a deadly threat for millions of people worldwide. However, the use of synthetic insecticides to control Culicidae may lead to resistance, high operational costs and adverse non-target effects. Nowadays, plant-borne mosquitocides may serve as suitable alternative in the… Read more »
Comparative inhibitory effects of Thymus vulgaris L. essential oil against Staphylococcus aureus, Listeria monocytogenes and mesophilic starter co-culture in cheese-mimicking models
de Carvalho RJ, de Souza GT, Honório VG, de Sousa JP, da Conceição ML, Maganani M, de Souza EL
Food Microbiology, 2015