Renal elimination of verbenols in man following experimental alpha-pinene inhalation exposure

Levin JOEriksson KFalk ALöf A
International Archives of Occupational and Environmental Health, 1992


ABSTRACT:

The renal elimination of verbenols after experimental exposure to (+) and (-)alpha-pinene was studied in humans following exposure to 10, 225, and 450 mg.m-3 terpene in an exposure chamber. The pulmonary uptake was about 60%. About 8% was eliminated unchanged in exhaled air. Depending on the exposure level, about 1%-4% of the total uptake was eliminated as cis- and trans-verbenol. Most of the verbenols were eliminated within 20 h after a 2-h exposure. The renal excretion of unchanged alpha-pinene was less than 0.001%.

CITATION:

Levin JOEriksson KFalk A, et al. Renal elimination of verbenols in man following experimental alpha-pinene inhalation exposure. Int Arch Occup Environ Health. 1992;63(8):571-573.


Click for Full Text Access

 

(Visited 193 times, 1 visits today)